"Prosci"

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Anti-HAND1 Rabbit Polyclonal Antibody

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Anti-SLC25A4 Rabbit Polyclonal Antibody

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Anti-CLPTM1 Rabbit Polyclonal Antibody

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Anti-CK-301 Recombinant Antibody

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The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target.

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Anti-Il9 Recombinant Antibody [Clone: D9302C12]

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FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives. FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics. In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly.

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The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin 1 may act as an autocrine negative growth factor that regulates cell proliferation. It also may regulate cell apoptosis and cell differentiation. It binds beta-galactoside, CD45, CD3 and CD4. Galectin 1 inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. It is found in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney, placenta and hematopoietic cells.

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The HIB19 monoclonal antibody reacts with a human 95 kDa transmembrane glycoprotein known as CD19, which is expressed by B lymphocytes during all the developmental stages, except for the terminally differentiated plasma cells. CD19 is also expressed on follicular dendritic cells, and seems to ensure the regulation of B lymphocytes proliferation. CD19, CD21, CD81, MHC class II, and Leu13 can bind together and form a complex which associates with the B cell receptor (BCR) on the surface of B lymphocytes and facilitates the signal transduction.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

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TRPM2 is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death.The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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Located on chromosome 16, the FLJ31875 gene encodes a hypothetical protein.

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Anti-CHODL Rabbit Polyclonal Antibody

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Polyclonal, Host: Goat; Target Species: Human; Immunogen: POU6F2 antibody was raised against a 13 amino acid synthetic peptide near the N-Terminus of POU6F2; Applications: ELISA,Western blotting

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MOX1 Antibody: MOX1, also known as MEOX1, is a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes that is first expressed during gastrulation in the early mesoderm and later in presomitic mesoderm, early somites, dermomyotome and sclerotome. Both MOX1 and the related protein MOX2 are required for proper gene expression in all somitic compartments. MOX1 is an upstream regulator of the transcription factors Bapx1, Tbx18, and Uncx and is thus part of a regulatory circuit that functions in the maintenance of rostrocaudal sclerotome polarity and axial skeleton formation.

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Anti-FPA-144 Recombinant Antibody

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Foxp4 is a member of the murine forkhead family of transcription factors. It is expressed exclusively in the epithelial cells of the developing intestine, where, in late development, it is expressed in a gradient along the longitudinal axis of the villi.