"Peprotech"

Supplier: Peprotech

C1 inhibitor is a member of the serpin family of structurally related proteins, and is the primary regulator of the immune complement system. C1 inhibitor is a protease inhibitor that functions to inhibit the complement system in order to prevent over-activation or spontaneous activation. Inhibition is achieved by binding to and irreversibly inhibiting the C1r and C1s proteases of the C1 complex, which has the effect of shutting down all subsequent downstream events in the complement activation cascade. C1 inhibitor can also inhibit various other proteases, including Kallikrein, Factor XIa, and Factor XIIa. Deficiencies in C1 inhibitor are the primary cause of hereditary angioedema (HAE, hereditary angioneurotic edema), a disease characterized by edema in the respiratory and gastrointestinal tracts. In certain clinical situations, the direct administration of C1 inhibitor can be used to treat HAE and certain other conditions. Recombinant Human C1 Inhibitor is a highly glycosylated glycoprotein containing 478 amino acid residues (52.8kDa), corresponding to amino acids 23 – 500 of the C1 inhibitor precursor, and is fully functional in its ability to inhibit the C1 complex. Glycosylated C1 Inhibitor migrates at an apparent molecular weight of approximately 80-90 kDa by SDS PAGE analysis under reducing conditions.

Supplier: Peprotech

RELMβ (Resistin-like molecule β/FIZZ2) is a disulfide-linked, homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known, but it has been suggested that it plays a regulatory role during inflammation, and may also act to establish links among adipose tissue, the intestine and the liver. Interestingly, the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokines, resistin and RELMα. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant Human RELMβ is a 19.0 kDa protein, consisting of two identical 89 amino acid polypeptide chains linked by a single disulfide bond.

Supplier: Peprotech

Animal-Free Human FGF-19 Recombinant Protein, Purity: >95% SDS and HPLC, Source: E.coli, Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells, 100-150 ng/ml, Synonyms: Fib

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human TL-1A. Anti­Human TL-1A­specific antibody was purified by affinity chromatography employing an immobilized Human TL-1A matrix.

Supplier: Peprotech

GMF-β is a brain-specific protein that belongs to the actin-binding proteins ADF structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines. Recombinant Human GMF-β is a 16.5 kDa globular protein containing 141 amino acid residues, including one intramolecular disulfide bond.

Supplier: Peprotech

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acid residues.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human BD-1. Anti­Human BD-1­specific antibody was purified by affinity chromatography employing an immobilized Human BD-1 matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human FGF-4. Anti­Human FGF-4­specific antibody was purified by affinity chromatography employing an immobilized Human FGF-4 matrix.

Supplier: Peprotech

Recombinant Murine R-Spondin-1, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Cross Reactivity: Mouse, R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells, Synonyms: Roof plate-specific Spondin-1, Size: 500UG

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human/Murine/Rat BMP-2. Anti­Human/Murine/Rat BMP-2­specific antibody was purified by affinity chromatography employing an immobilized Human/Murine/Rat BMP-2 matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human IL-17E. Anti­Human IL-17E­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant Human GRO-α/MGSA (CXCL1) is a 7.8 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human ApoE3. Anti­Human ApoE3­specific antibody was purified by affinity chromatography employing an immobilized Human ApoE3 matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Human sRANK Receptor. Anti­Human sRANK Receptor­specific antibody was purified by affinity chromatography employing an immobilized Human sRANK Receptor matrix.

Supplier: Peprotech

Produced from sera of rabbits immunized with highly pure Recombinant Rat GM-CSF. Anti­Rat GM-CSF­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: Peprotech

Recombinant Human B7-H2 Fc, Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses, Source: CHO cells, Determined by its ability to induce adhesion in Jurkat cells activated by immobilized anti-CD3, Synonyms: B7-like protein Gl50, CD275, Size: 100UG