"Other Essentials"

Supplier: Biosensis

CNTF is a survival promoting factor for different types of neurons in vitro and in vivo. The essential structural features for the biological function of human CNTF were investigated by Thier, M. et al. They showed that deletion of 14 N-terminal and 18 C-terminal amino acids significantly increased bioactivity compared to wild-type CNTF. FUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. SUBUNIT: Homodimer. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Nervous system. PHARMACEUTICAL: CNTF is being tested under the name Axokine by Regeneron Pharmaceuticals for treatment of human motor neuron diseases, such as amyotrophic lateral sclerosis (ALS). As it induces substantial weight loss, preferentially of fat as opposed to lean body mass, it is being used for obesity treatment. SIMILARITY: Belongs to the CNTF family.

Supplier: Genetex

Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. Phosphorylation of I-kB by IkB kinase (IKK) complex leads to degradation of I-kB and activation of NF-kB. The IKK complex contains IKKa,IKKb, and IKKg. A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-kB-activating kinase), and T2K. NAK/TBK1 activates IKKb through direct phosphorylation. NAK/TBK1is activated by growth factors and PMA and mediates IKK and NF-kB activation in response to growth factors. NAK/TBK1 functions upstream of NIK and the IKK complex. NAK/TBK1 is also critical in protecting embryonic liver from apoptosis.

Supplier: Prosci

SENP2 is an enzyme that belongs to the peptidase C48 family

Supplier: ACL Staticide

Staticide® Acrylic Conformal Coating is ideal for providing insulation against high-voltage arcing and corona shorts

Supplier: Hanna

This chemical test kit measures total hardness as CaCO₃ by titration with EDTA. It includes all of the reagents and equipment necessary to perform approximately 100 tests.

Supplier: Enzo Life Sciences

Produced in E. coli.

Supplier: Electron Microscopy Sciences

Used for counting fibrous dust including asbestos or glass fibers.

Supplier: Remco Products

The dough cutter/scraper cuts and handles dough, removes sticky messes that would clog a brush, and easily deals with burnt-on foods on tables and cutting boards.

Supplier: Mettler Toledo

This universal well designed meter is the perfect economical choice for a wide range of applications.

Supplier: VWR International

Durable plated-steel ring clamp holds labware securely on stands for heating or experiment setups.

Supplier: American Scientific

Elevate your weather monitoring with our 4-in-1 handheld digital anemometer.

Supplier: PHC Corporation

The PHCbi plant growth chamber is an exceptional unit suitable for a wide range of applications.

Supplier: LONZA PHARMA - BIOSCIENCE CA

Human renal cells include cells isolated from various normal human kidney tissue specific to each cell type.Human Renal Proximal Tubule Cells are isolated from the proximal tubule and are ideal for drug transporter studies.

Supplier: Rockland Immunochemical

Human TGF beta 1 AccuSignal ELISA Kit

Supplier: CELLTREAT Scientific Products

The ideal device for repetitive pipetting of volumes over 1 ml, particularly in tight quarters.

Supplier: Rockland Immunochemical

Human sVEGFR1 - sFLT1 AccuSignal ELISA Kit