"Genscript"

Supplier: Genscript

This endotoxin detection system is intended for use as an in vitro end-product endotoxin test for human and animal parenteral drugs, biological products and medical devices.

Supplier: Genscript

A Camelid VHH Antibody (also called single-domain antibody, sdAb or Nanobody by Ablynx) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody. Like a whole antibody, it is able to bind selectively to a specific antigen. VHH antibodies allow a broad range of applications in biotechnical as well as therapeutic use due to their small size, simple production and high affinity.

Supplier: Genscript

Payloads are the important components of antibody-drug conjugates (ADCs). The most commonly used ADC payloads are MMAE, DM1, and DXd. ADC pharmacokinetic (PK) studies include free payload analysis, conjugated antibody analysis, and total antibody analysis via ligand-binding assay (LBA) and LC-MS/MS assay. The anti-payload antibody is a useful reagent in PK assay for determining conjugated antibodies. It can be used as a capture antibody to determine the conjugated antibody in LBA assay or through immunocapture to enrich the ADC sample in LC-MS/MS assay. The DM1, also known as mertansine, is a microtubule polymerization inhibitor. Trastuzumab emtansine (T-DM1), composed of trastuzumab conjugated to DM1, is a type of targeted cancer drug for breast cancer treatment. T-DM1 is targeted toward HER2 (ERBB2) positive breast cancer.

Supplier: Genscript

The product is specific for bevacizumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01975-40, anti-bevacizumab antibody (4H1), mAb, mouse.

Supplier: Genscript

The specificity of the antibody is defined as the ratio of antigen concentration to cross-reactant concentration at 50% inhibition of maximum binding.

Supplier: Genscript

CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. It plays an important role in cell proliferation and cytokine production and promotion of T-cell survival. It also enhances the production of IL-4 and IL-10 in T cells in conjunction with TCR/CD3 ligation and CD40L co-stimulation.

Supplier: Genscript

Ustekinumab with trade name Stelara, is an FDA-approved drug to Crohn's disease, Ulcerative Colitis, Plaque Psoriasis and Psoriatic Arthritis, targeting both interleukins (IL)-12 and IL-23. Ustekinumab is a fully human immunoglobulin G1 kappa mAb that binds to IL-12 and IL-23. Ustekinumab binds to the p40 subunit common to IL-12 and IL-23 and prevents their interaction with the IL-12 receptor β1 subunit of the IL-12 and IL-23 receptor complexes, thereby disrupting the proinflammatory pathway. Anti-Ustekinumab Antibody (9A5), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Ustekinumab.

Supplier: Genscript

GenScript MonoRab™ Beta-Actin Antibody, mAb, Rabbit reacts with mouse, human, hamster, and rat. It has not yet been tested in other species.

Supplier: Genscript

To enable fast and efficient purification of antibody and epitope-tagged proteins, GenScript provides super paramagnetic magnetic beads. GenScript magnetic beads are coated with recombinant protein ligands that enable highly specific affinity binding to antibodies and epitope-tagged proteins.

Supplier: Genscript

GenScript Purified Mouse IgG (Whole Molecule) Control is highly purified from normal mouse serum through Protein A chromatography.GenScript Purified Mouse IgG (Whole Molecule) Control is suitable to be used as control, standard, blocking agent, or coating protein in a variety of assays, including ELISA, immunobloting (Dot blot and Western blot), immunoprecipitation, immunodiffusion, and immunoelectrophoresis.It may also be used as antigen or ligand in immunochemical conjugation reaction.

Supplier: Genscript

GenScript His-tag antibody [Biotin], pAb, Rabbit specifically reacts with fusion proteins containing His tagged fusion proteins.

Supplier: Genscript

The product is specific for Pembrolizumab. This antibody serves as an excellent positive control for Pembrolizumab immunogenicity (ADA) assays.

Supplier: Genscript

THE™ HA Tag antibody [HRP], mAb, Mouse recognizes C-terminal, N-terminal and internal HA tagged fusion proteins.

Supplier: Genscript

THE™ Anti-GST Monoclonal antibody (Mouse) recognizes GST localized at the C-terminal, N-terminal and internal region ofGST-tagged fusion proteins.

Supplier: Genscript

THE™ NWSHPQFEK Tag antibody [FITC], mAb, Mouse recognizes N-terminal and C-terminal Strep II tagged fusion proteins.

Supplier: Genscript

The product is specific for daratumumab. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody Genscript, A01997 anti-daratumumab antibody (6A3).