Supplier: Bachem Americas

These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

These dipeptide building blocks containing Ser- or Thr-derived oxazolidines (pseudoprolines) proved to be versatile tools for overcoming some intrinsic problems in the field of peptide chemistry. The presence of pseudoprolines within a peptide sequence results in the disruption of β-sheet structures considered as a source of intermolecular aggregation during chain elongation, thus increasing solvation and coupling kinetics in peptide assembly. Therefore, use of pseudoprolines offer new possibilities for accessing large peptides by convergent strategies and chemoselective ligation techniques. Moreover, incorporation of a pseudoproline unit facilitates cyclization of peptides.

Supplier: Bachem Americas

Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).

Supplier: Bachem Americas

Substrates for measuring the chymotryptic, PGPH, and tryptic acitivity of the 20S or 26S proteasome. See also the thrombin substrate I-1140.

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Sequence: Ac-Arg-Gly-Lys(Ac)-AMC
Synonym(s): Ac-RGK(Ac)-AMC

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Z-PLG.

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Sequence: Boc-Orn(Fmoc)-OH

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Sequence: H-Dab(Boc)-OH

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The integrin-binding heptapeptideGRGDSPC can be easily linked to carriers or surfaces.

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The hexapeptide GRGDSP is used for the affinity purification of fibronectin receptors, as it contains the RGD integrin recognition site of the fibronectin cell binding domain. The immobilized peptide promotes mouse blastocyst attachment and outgrowth, whereas in solution, GRGDSP is a reversible inhibitor of entactin-mediated blastocyst outgrowth.

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Sequence: Boc-Asn-OH

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Sequence: Boc-D-2-Nal-OH

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Sequence: Boc-Phe-Leu-Phe-Leu-Phe-OH
Synonym(s): Boc-FLFLF#Boc-2

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Sequence: Boc-Arg(Mtr)-OH

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Sequence: Boc-Tyr-OH

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Sequence: Boc-p-amino-Phe(Fmoc)-OH

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Sequence: Boc-D-Lys(Fmoc)-OH

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For Boc-dipeptides Boc-Xaa-Gly-OH and Boc-Xaa-Pro-OH, which can be used as building blocks during Boc-SPPS, please see the product family 'Boc-Dipeptide Building Blocks' in the 'Amino Acid Derivatives' section. This family also includes short protected peptide fragments suitable for solution synthesis and preparation of enzyme substrates and inhibitors.

Supplier: Bachem Americas

Sequence: 3-Palmitoyl-sn-glycerol
Synonym(s): L-α-Palmitin

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MEGA-10
CAS: 85261-20-7
Formula: C17H35NO6
M.W: 349.47
Storage temp.: -20 ± 5 °C

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Sequence: 1,2-Dilauroyl-sn-glycero-3-phosphocholine
Synonym(s): DLPC#L-β,γ-Dilauroyl-α-lecithin

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Sequence: 1,3-Dipalmitoyl-glycerol
Synonym(s): α,γ-Dipalmitin

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Sequence: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
Synonym(s): DPPC#L-β,γ-Dipalmitoyl-α-lecithin

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Sequence: 1,2-Dimyristoyl-sn-glycerol
Synonym(s): D-α,β-Dimyristin

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Sequence: 1,2-O-Dioctadecyl-sn-glycerol
Synonym(s): D-α,β-Dioctadecyl-glycerol

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Sequence: 1-Methyl-1H-imidazole-2-carboxylic acid

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Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It corresponds to the Swedish-mutated (JMV2236) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is more selectively cleaved by BACE1 and BACE2 than by cathepsin D, a disintegrin and metalloprotease 10 (ADAM10), tumor necrosis α-converting enzyme (TACE), presenilin-1 (PS1), or presenilin-2 (PS2).

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Sequence: 1,2-Distearoyl-sn-glycero-3-phosphocholine
Synonym(s): DSPC#L-β,γ-Distearoyl-α-lecithin

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Sequence: 1-O-Hexadecyl-sn-glycero-3-phosphocholine

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Sequence: Boc-N-Me-Phe-OH