Mouse Recombinant PDGF-BB (from E. coli cells)
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Product Details & Documents
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
- High quality
- Low endotoxin
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PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
Caution: For research use only.
Spécifications
Spécifications
- Type de conditionnement:Vial
- Taille:500 µg
- Protease-free:N
- Purity:≥95%
- Source:E. coli
- Molecular weight:12.4/24.7 kDa
- Nuclease-free:N
- Protein/peptide type:Recombinant
- Endotoxin content:Endotoxin LAL (EU/µg) ≤1
- Gene ID:P31240
- Formulation:10 mM sodium citrate, pH 3.0
- Endotoxin-free:N
- Species:Mouse
- Protein/peptide name:PDGF-BB
- Protein synonyms:GDGF|ODGF
- Protein Function:Cytokine
- Endotoxin level:Low
- Grade:RUO
- Sequence:MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- Biological activity:Bioactivity assay: 3T3 cell proliferation; ED50 ≤2 ng/ml; Bioactivity ≥5.0×10⁵ units/mg
- Shipping temperature:RT
- Cat. No.:77752-486
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Storage conditions:–20 °C
- Carrier-free:Y
- Conjugation:Unconjugated
- Animal-free:N
Spécifications
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Catalog #: CA21905-026
Supplier: Kimberly-Clark