Mouse Recombinant PDGF-BB (from E. coli cells)
- L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
- Return Policy
Product Details & Documents
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
- High quality
- Low endotoxin
- Affordable
PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
Caution: For research use only.
Spécifications
Spécifications
- Type de conditionnement:Vial
- Taille:100 µg
- Protease-free:N
- Purity:≥95%
- Source:E. coli
- Molecular weight:12.4/24.7 kDa
- Nuclease-free:N
- Protein/peptide type:Recombinant
- Endotoxin content:Endotoxin LAL (EU/µg) ≤1
- Gene ID:P31240
- Formulation:10 mM sodium citrate, pH 3.0
- Endotoxin-free:N
- Species:Mouse
- Protein/peptide name:PDGF-BB
- Protein synonyms:GDGF|ODGF
- Protein Function:Cytokine
- Endotoxin level:Low
- Grade:RUO
- Sequence:MSLGSLAAAE PAVIAECKTR TEVFQISRNL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRASQVQMRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETIVTPRPVT
- Biological activity:Bioactivity assay: 3T3 cell proliferation; ED50 ≤2 ng/ml; Bioactivity ≥5.0×10⁵ units/mg
- Shipping temperature:Room temperature
- Cat. No.:77752-480
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Storage conditions:–20 °C
- Carrier-free:Y
- Conjugation:Unconjugated
- Animal-free:N
Spécifications
Les recommandations seront personnalisées selon vos préférences d’achat uniquement si vous avez activé "Améliorer mon expérience d’achat" dans la page "Informations personnelles".
Sinon, vous recevrez des recommandations génériques.
Catalogue #: CA21905-026
Supplier: Kimberly-Clark