Duplex Dnase

An engineered double-strand specific DNA endonuclease, dsDNase preferentially degrades double-stranded DNA (dsDNA) over single-stranded DNA (ssDNA) or RNA.

• Specifically degrades dsDNA in the presence of ssDNA
• Cleaves DNA strand of DNA:RNA hybrid duplex
• Isolated from a recombinant sourceRNase-free
• Supplied with 10X reaction buffer

This specificity toward dsDNA allows the enzyme to degrade contaminating dsDNA while maintaining the integrity of single stranded DNA molecules such as primers and probes within PCR mixes, allowing for efficient decontamination of PCR master mixes. Moreover, dsDNase displays the unique property of cleaving the DNA strand of a DNA:RNA hybrid duplex.

Concentration: 2000 units/ml