Proteomic Grade Detergent Solutions

Many commercial grade detergents contain elevated levels of sulfhydryl oxidizing agents, peroxides, salts and carbonyl compounds.

Our Proteomic Grade Detergent Solutions contain reduced peroxides and carbonyl compounds. In addition, the detergents have less than 50 μS conductivity. These detergents are offered as 10% aqueous solutions, sealed under inert gas and are suitable for protein applications. These non-ionic detergents are suitable for isolating membrane-protein complexes.

G-Biosciences Proteomic Grade Detergent Solutions include: Triton® X-100, Triton® X-114, Brij® 35, Brij® 58, Tween® 20, Tween® 80, and Nonidet® P-40 Substitute. A variety pack, perfect for trial and optimization, is also available. The pack contains one 10 ml vial of all seven proteomic grade detergents, as well as 1 g samples of one of our Zwitterionic detergents (CHAPS) and one of our non-detergent sulfobetaines (NDSB 201).

The proteins that are isolated with these detergents are highly susceptible to contaminating peroxides and carbonyls. The peroxides will oxidize proteins and the carbonyl groups will form Schiff’s bases with the proteins that interfere with its structure.

 : Accessories not included.