Non-Ionic Detergent Solutions

Non-ionic detergents have a hydrophilic head group that is uncharged and are preferred for their ability to break lipid-lipid and lipid-protein interactions.

The non-ionic deteregents are supplied as a general Research Grade, Proteomic Grade (PG) Solutions and 2D-Detergents™. The Proteomic Grade (PG) Solutions have ultra low aldehyde (<100 μM) and peroxide (<50 μM) concentrations to reduce the effects of peroxidase and carbonyl compounds that negatively interact with membrane proteins. The 2D-Detergents™ have low conductivity (<10 μS) and ultra low aldehyde (<100 μM) and peroxide (<50 μM) concentrations.

G-Biosciences Non-Ionic Detergent Solutions include: Triton® X-100, Triton® X-114, Brij® 35, Brij® 58, Tween® 20, Tween® 80, Nonidet® P-40 Substitute, Octyl ß Glucoside, MEGA 8, MEGA 9, MEGA 10, BigCHAP, and Deoxy Big CHAP.

They have limited ability to break protein-protein interactions and are often referred to as non-denaturing detergents and are used to isolate biologically active membrane proteins.

Ordering information: Accessories not included.