VU0155041 ≥99% positive allosteric mGluR4 agonist
À propos de cet article
Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Available in water-soluble form - please see VU0155041 sodium salt (ab120248).
Caution: All products are FOR RESEARCH USE ONLY. PRODUCTS ARE NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Customer is granted a limited use non-exclusive licence for its own internal research. Any control manufacturer supplies with a Product is limited to use only to validate the relevant Product. By using the Product, Customers agree not to attempt to reverse engineer or otherwise perform any compositional, structural, functional or other analyses directed to learning the methodology, formulae, sequences, processes, make-up or production of any of the Products or portions thereof.
- CAS Number:1093757-42-6
- Molecular Weight:316.2 g/mol
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Product Details & Documents
Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Available in water-soluble form - please see VU0155041 sodium salt (ab120248).
Caution: All products are FOR RESEARCH USE ONLY. PRODUCTS ARE NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Customer is granted a limited use non-exclusive licence for its own internal research. Any control manufacturer supplies with a Product is limited to use only to validate the relevant Product. By using the Product, Customers agree not to attempt to reverse engineer or otherwise perform any compositional, structural, functional or other analyses directed to learning the methodology, formulae, sequences, processes, make-up or production of any of the Products or portions thereof.
- CAS Number:1093757-42-6
- Molecular Weight:316.2 g/mol
Specifications for Product Family
Résultats des tests de spécification
- Constituents::100% (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
Product Family Options
Informations sur le produit
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Catalog #: CA21905-026
Supplier: Kimberly-Clark