Mouse Recombinant IL-1A (from E. coli)
À propos de cet article
Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
High quality
Low endotoxin
Affordable
Caution: For research use only.
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Product Details & Documents
Interleukin 1 alpha (IL-1α) is expressed by epithelial cells, activated macrophages, neutrophils, and endothelial cells to regulate immune responses. IL-1α signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MYD88) signaling pathway, which contains the cytoplasmic toll/IL-1 receptor (TIR) domain adapter. IL-1α and the independently regulated IL-1β protein have overlapping proinflammatory activities to induce adhesion molecule expression on epithelial cells, control fever induction, initiate rheumatoid arthritis, and promote septic shock.
High quality
Low endotoxin
Affordable
Caution: For research use only.
Specifications for Product Family
Spécifications
Spécifications
- Catalog No:
- 77752-760
- 77752-762
- 77752-764
- 77752-766
- 77752-768
- Protein/peptide name:
- IL-1A
- IL-1A
- IL-1A
- IL-1A
- IL-1A
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Cytokine
- Species:
- Mouse
- Mouse
- Mouse
- Mouse
- Mouse
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- P01582
- P01582
- P01582
- P01582
- P01582
- Sequence:
- MSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQIS
- MSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQIS
- MSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQIS
- MSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQIS
- MSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQIS
- Protease-free:
- N
- N
- N
- N
- N
- Animal-free:
- N
- N
- N
- N
- N
- Nuclease-free:
- N
- N
- N
- N
- N
- Carrier-free:
- Y
- Y
- Y
- Y
- Y
- Endotoxin-free:
- N
- N
- N
- N
- N
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Endotoxin LAL (EU/µg) ≤0.1
- Biological activity:
- Bioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mg
- Bioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mg
- Bioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mg
- Bioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mg
- Bioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mg
- Purity:
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- ≥95%
- Grade:
- RUO
- RUO
- RUO
- RUO
- RUO
- Formulation:
- 10 mM sodium phosphate, pH 7.5
- 10 mM sodium phosphate, pH 7.5
- 10 mM sodium phosphate, pH 7.5
- 10 mM sodium phosphate, pH 7.5
- 10 mM sodium phosphate, pH 7.5
- Molecular weight:
- 18.1 kDa
- 18.1 kDa
- 18.1 kDa
- 18.1 kDa
- 18.1 kDa
- Reconstitution instructions:
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Sterile water at 0.1 mg/ml
- Storage conditions:
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- –20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- RT
- Tested applications:
- Bioassay
- Bioassay
- Bioassay
- Bioassay
- Bioassay
Spécifications
Product Family Options
Informations sur le produit
- Type de conditionnementTailleAvailabilityPrice
- L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.77752-760Protein/peptide nameIL-1AProtein/peptide typeRecombinantProtein FunctionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP01582SequenceMSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQISProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1Biological activityBioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, pH 7.5Molecular weight18.1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.77752-762Protein/peptide nameIL-1AProtein/peptide typeRecombinantProtein FunctionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP01582SequenceMSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQISProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1Biological activityBioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, pH 7.5Molecular weight18.1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.77752-764Protein/peptide nameIL-1AProtein/peptide typeRecombinantProtein FunctionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP01582SequenceMSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQISProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1Biological activityBioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, pH 7.5Molecular weight18.1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.77752-766Protein/peptide nameIL-1AProtein/peptide typeRecombinantProtein FunctionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP01582SequenceMSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQISProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1Biological activityBioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, pH 7.5Molecular weight18.1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay - L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.77752-768Protein/peptide nameIL-1AProtein/peptide typeRecombinantProtein FunctionCytokineSpeciesMouseSourceE. coliConjugationUnconjugatedGene IDP01582SequenceMSAPYTYQSD LRYKLMKLVR QKFVMNDSLN QTIYQDVDKH YLSTTWLNDL QQEVKFDMYA YSSGGDDSKY PVTLKISDSQ LFVSAQGEDQ PVLLKELPET PKLITGSETD LIFFWKSINS KNYFTSAAYP ELFIATKEQS RVHLARGLPS MTDFQISProtease-freeNAnimal-freeNNuclease-freeNCarrier-freeYEndotoxin-freeNEndotoxin levelLowEndotoxin contentEndotoxin LAL (EU/µg) ≤0.1Biological activityBioactivity assay: D10.G4.1 proliferation; ED50 ≤0.01 ng/ml; Bioactivity ≥1.0×10⁸ units/mgPurity≥95%GradeRUOFormulation10 mM sodium phosphate, pH 7.5Molecular weight18.1 kDaReconstitution instructionsSterile water at 0.1 mg/mlStorage conditions–20 °CShipping temperatureRTTested applicationsBioassay
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