The CRISPRclean® stranded total RNA prep with rRNA depletion (HMR) is a total RNA library prep leveraging a CRISPR-powered workflow facilitating the detection of lower expressing and biologically relevant transcripts from complex samples.

• Efficient multi-species depletion using CRISPR-Cas9 technology in a single tube
• Enhances detection of biologically relevant, low-expressing transcripts
• Optimized library prep and depletion workflow ensures high-quality transcript representation
• Achieve consistent full-length, uniform transcript coverage with high library complexity
• Complete workflows in just one day: 7.5 hours assay with 3 hours of hands-on time

Specific, unbiased rRNA depletion and library prep for RNA-Seq. In RNA samples, up to 90% consists of ribosomal RNA. Failing to remove these abundant rRNA sequences during transcriptome sequencing reduces sequencing capacity and hinders the detection of biologically relevant, low-expressing transcripts. Discover how CRISPRclean® enhances research by efficiently removing rRNA.