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Specifications
- Protein/peptide type:Recombinant
- Source:CHO cells
- Species:Human
- Size:1000 µg
- Protein synonyms:EP|Epoetin|Erythropoietin
- Protein/peptide name:EPO
- Purity:≥95%
- Cat. no.:MSPP-780071997
Specifications
About this item
The principal physiological regulator of erythropoiesis, Erythropoietin (EPO) is a glycoprotein growth factor that is produced primarily in the kidney in response to hypoxia or anemia. EPO promotes erythropoiesis by binding to a homodimeric cell surface receptor that activates JAK2/STAT5, PI3K/AKT, and MAPK pathways, and stimulates the proliferation and differentiation of erythroid progenitor cells (Jelkmann. Transfus Med Hemother, 2013; Kuhrt and Wojchowski. Blood, 2015).