SMALP Screening Set

Membrane proteins and their composition are as versatile as the whole cell membrane itself. For this reason, it is impossible to predict with 100% accuracy which SMALP product is best suited for the solubilization and subsequent preparation of your membrane protein of interest. We offer this SMALP Screening Kit that consists of our four individual SMAs. This way, you can conveniently screen for the best SMA for your protein before scaling up your assay. In case you would like to extend your polymer screening beyond the reaches of SMA, we offer our Synthetic Nanodisc Screening Kit, which covers both SMA and DIBMA.

SMALP 300:
State: Lyophilized Powder, to be solved with water
Polymer styrene-to-maleic anhydride ratio: 3:1
Molecular weight: 10,000 Da
pH after solving: 7.5
Solubility: 35 %
Divalent cationic tolerance: < 5 mM
Color: Colorless
Odor: Odorless
Freeze-thaw stable?: Yes

SMALP 200:
State: Lyophilized Powder, to be solved with water
Polymer styrene-to-maleic anhydride ratio: 2:1
Molecular weight: 6,500 Da
pH after solving: 7.5
Solubility: 40 %
Divalent cationic tolerance: < 5 mM
Color: Yellowish
Odor: Odorless
Freeze-thaw stable?: Yes
Other noteworthy feature: Most commonly used SMA

SMALP 140:
State: Lyophilized Powder, to be solved with water
Polymer styrene-to-maleic anhydride ratio: 1.4:1
Molecular weight: 5000 Da
pH after solving: 7.5
Solubility: 45 %
Divalent cationic tolerance: < 5 mM
Color: Amber
Odor: Odorless
Freeze-thaw stable?: Yes

SMALP 140 I:
State: Lyophilized Powder, to be solved with water
Polymer styrene-to-maleic anhydride ratio: 1.4:1
Molecular weight: 5000 Da
pH after solving: 7.5
Solubility: 45 %
Divalent cationic tolerance: < 5 mM
Color: Amber
Odor: Odorless
Freeze-thaw stable?: Yes

 : Shipping Temperature: Ambient temperature. Storage of lyophilized copolymer: -20°C for several years. Storage of dissolved copolymer: 2-8°C for several day.