The alpha-Lytic Protease (aLP) cleaves after Threonine (T), Alanine (A), Serine (S) and Valine (V) residues.

• Digestion of proteins for proteomic analysis by mass spectrometry
• Suitable for both in-gel and solution digests
• Optimal activity and stability for up to 24 months
• Site-specific identification and quantitation of SUMO modifications under native conditions

Its specificity makes it an orthogonal and alternative protease to others commonly used in proteomics applications, including trypsin and chymotrypsin. Peptides generated by aLP are of similar average length to those of Trypsin.