Mouse Recombinant VEGF 165 (from E. coli)
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Product Details & Documents
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Murine VEGF 165 is a 39.0 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
- Animal-free
Specifications
Specifications
- Taille:50 µg
- Protein/peptide name:VEGF 165
- Protein synonyms:Vascular Endothelial Growth Factor165|VEGF-A|Glioma-derived endothelial cell mitogen|Folliculostellate cell-derived growth factor
- Purity:98%
- Endotoxin level:Low
- Sequence:MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
- Source:E. coli
- Biological activity:Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/ml.
- Molecular weight:39 kDa
- Shipping temperature:Ambient
- Cat. No.:76303-664
- Protein/peptide type:Recombinant
- Gene ID:22339
- Formulation:Lyophilized
- Conjugation:Unconjugated
- Species:Mouse
- Animal-free:Y
Specifications
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Catalog #: CA21905-026
Supplier: Kimberly-Clark