Human Recombinant GDF-3 (from E. coli)
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Product Details & Documents
GDF-3 is a member of the TGF-beta superfamily of growth and differentiation factors, and is highly homologous to GDF-9. Unlike most TGF-beta family members, GDF-3 and GDF-9 are not disulfide-linked dimers. GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue. The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia that characterizes Type 2 diabetes. Recombinant Human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains.
- Animal-free
Spécifications
Spécifications
- Taille:50 µg
- Protein/peptide name:GDF-3
- Protein synonyms:Vgr-2|Growth/Differentiation Factor-3|UNQ2222/PRO248
- Purity:98%
- Endotoxin level:Low
- Sequence:AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCG
- Source:E. coli
- Biological activity:Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 100-150 ng/ml.
- Molecular weight:26 kDa
- Shipping temperature:Ambient
- Cat. No.:76303-592
- Protein/peptide type:Recombinant
- Gene ID:9573
- Formulation:Lyophilized
- Conjugation:Unconjugated
- Species:Human
- Animal-free:Y
Spécifications
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Catalogue #: CA21905-026
Supplier: Kimberly-Clark