LiChrospher® is the name given to reliable and versatile traditionally produced spherical silica carriers. LiChrospher® silica carriers are available in a number of different modifications. The polar modified phases LiChrospher® CN, LiChrospher® NH₂ and LiChrospher® Diol as well as LiChrospher® Si with no modification are best for normal phase HPLC.

LiChrospher® Si 60 is a versatile HPLC spherical silica sorbent with a pore diameter of 60 Å and a particle size of 5 µm for normal phase chromatography.

LiChrospher® CN has polar and hydrophobic properties, thus can be used as less polar alternative to LiChrospher® Si 60 in normal phase applications or as less hyfrophobic alternative to LiChrospher® RP-8 in reversed phase applications.

LiChrospher® NH₂ posses polar and hydrophobic properties and can be used for normal phase, reversed phase and ion exchange chromatography. Typical applications are the separations of carbohydrates by reversed phase chromatography or the separsation of nucleotides by ion exhange chromatography.

LiChrospher® Diol has polar and hydrophobic properties, thus can be used as less polar alternative to LiChrospher® Si 60 in normal phase applications or as less hydrophobic alternative to LiChrospher® RP-8 in reversed phase applications. LiChrospher® Diol is also suitable for exclusion chromatography.

LiChrospher® RP-18 and LiChrospher® RP-18 endcapped are reliable and versatile traditionally produced spherical silica gel carriers with C-18 reversed phase properties. They are well suited for the separation of neutral, acidic and weak basic compounds.
LiChrospher® RP-select B is a versatile traditionally produced spherical silica gel carrier with reversed phase properties and with the hydrophobicity of a C-8 phase. This carrier is very well suited for the separation of basic compounds, but with still good properties for the determination of neutral and acidic compounds.