Human Recombinant IL18 (from E. coli)

0.05 mg

Catalog # 75791-086

Supplier: Prosci

Fournisseur #: 92-246

Human Recombinant IL18 (from <i>E. coli</i>)

Catalog # 75791-086

Supplier: Prosci

CAS Number:

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Spécifications

CAS Number:

Price

$1,247.54

L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
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Product Details & Documents

Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon- gamma (IFN- gamma ) or type II interferon that plays an important role in activating the macrophages or other cells.

This recombinant protein can be used for biological assays. For research use only.

Spécifications

Taille:
0.05 mg
Protein/peptide name:
IL18
Protein synonyms:
IL-1g|IL-1 gamma|IL-1F4|MGC12320|Interferon gamma-inducing factor|Iboctadekin|GIF|Interleukin-1 gamma|IL1F4|IFN-gamma-inducing factor|Interleukin-18|IL-18
Purity:
> 95% as determined by reducing SDS-PAGE
Sequence:
Tyr37-Asp193
Source:
E. coli
Molecular weight:
18.2 kD
Cat. No.:
75791-086
Protein/peptide type:
Recombinant
Endotoxin content:
<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Storage conditions:
Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
Formulation:
Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications:
Bioassay
Species:
Human