Human Recombinant LMCD1 (from E. coli)

0.05 mg

Catalog # 75791-014

Supplier: Prosci

Fournisseur #: 92-210

Human Recombinant LMCD1 (from <i>E. coli</i>)

Catalog # 75791-014

Supplier: Prosci

CAS Number:

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CAS Number:

Price

$1,570.22

L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
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Product Details & Documents

LMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.

Fusion-Tag: N, C-6 His tag

This recombinant protein can be used for biological assays. For research use only.

Spécifications

Taille:
0.05 mg
Protein/peptide name:
LMCD1
Protein synonyms:
Dyxin|LMCD1|LIM and cysteine-rich domains protein 1
Purity:
> 95% as determined by reducing SDS-PAGE
Sequence:
Met1-Ser365
Source:
E. coli
Molecular weight:
44 kD
Cat. No.:
75791-014
Protein/peptide type:
Recombinant
Endotoxin content:
<0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Storage conditions:
Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Formulation:
Supplied as a 0.2 um filtered solution of 20mM PB，150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tag sequence:
N, C-6 His tag
Tested applications:
Bioassay
Species:
Human