Human Recombinant BDNF (from E. coli)
À propos de cet article
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical. Manufactured using all Animal-Free reagents.
- Carrier free
- Animal-free
MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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Product Details & Documents
BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical. Manufactured using all Animal-Free reagents.
- Carrier free
- Animal-free
MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Verified by N-terminal and Mass Spectrometry analyses (when applicable).
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
Spécifications
Spécifications
- Catalog No:
- 10781-784
- 10781-786
- 10781-788
- 10781-790
- 10781-792
- 10781-794
- Protein/peptide name:
- BDNF
- BDNF
- BDNF
- BDNF
- BDNF
- BDNF
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Species:
- Human
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Animal-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Endotoxin content:
- <0.1 ng/μg of protein (<1 EU/μg).
- <0.1 ng/μg of protein (<1 EU/μg).
- <0.1 ng/μg of protein (<1 EU/μg).
- <0.1 ng/μg of protein (<1 EU/μg).
- <0.1 ng/μg of protein (<1 EU/μg).
- <0.1 ng/μg of protein (<1 EU/μg).
- Biological activity:
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.
- Purity:
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Greater than 98% by SDS-PAGE gel and HPLC analyses.
- Formulation:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Storage conditions:
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- −20 °C
- Shipping temperature:
- RT
- RT
- RT
- RT
- RT
- RT
Spécifications
Product Family Options
Informations sur le produit
- TailleOriginAvailabilityPrice
- Supplier Number: AF-450-02-2UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
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Specifications
Cat. No.10781-784Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT - Supplier Number: AF-450-02-10UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
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Specifications
Cat. No.10781-786Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT - Supplier Number: AF-450-02-100UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-788Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT - Supplier Number: AF-450-02-250UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-790Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT - Supplier Number: AF-450-02-500UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-792Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT - Supplier Number: AF-450-02-1MGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-794Protein/peptide nameBDNFProtein/peptide typeRecombinantSpeciesHumanSourceE. coliAnimal-freeYEndotoxin content<0.1 ng/μg of protein (<1 EU/μg).Biological activityDetermined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0 μg/ml.PurityGreater than 98% by SDS-PAGE gel and HPLC analyses.FormulationLyophilizedStorage conditions−20 °CShipping temperatureRT
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Catalogue #: CA21905-026
Supplier: Kimberly-Clark