Human Recombinant NGF beta (from E. coli)

Human Recombinant NGF beta (from <i>E. coli</i>)

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β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.Manufactured using all Animal-Free reagents.

Carrier free
Animal-free

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
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Carrier free
Animal-free

SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications for Product Family

Spécifications

Catalog No:
10781-774
10781-776
10781-778
10781-780
10781-782

Protein/peptide name:
NGF beta
NGF beta
NGF beta
NGF beta
NGF beta

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Species:
Human
Human
Human
Human
Human

Source:
E. coli
E. coli
E. coli
E. coli
E. coli

Animal-free:
Y
Y
Y
Y
Y

Endotoxin content:
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).

Biological activity:
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.

Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Formulation:
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized

Storage conditions:
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C

Shipping temperature:
RT
RT
RT
RT
RT

Spécifications

Product Family Options

Informations sur le produit

Taille
Origin
Availability
Price
10781-774
20 µg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (20µG)
Each (20µG) - $314.04
$314.04
Each (20µG)
$314.04
La quantité minimale de commande est de 1
Supplier Number: AF-450-01-20UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10781-774
Protein/peptide name
NGF beta
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10781-776
100 µg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (100µG)
Each (100µG) - $654.48
$654.48
Each (100µG)
$654.48
La quantité minimale de commande est de 1
Supplier Number: AF-450-01-100UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10781-776
Protein/peptide name
NGF beta
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10781-778
250 µg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (250µG)
Each (250µG) - $1,121.65
$1,121.65
Each (250µG)
$1,121.65
La quantité minimale de commande est de 1
Supplier Number: AF-450-01-250UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10781-778
Protein/peptide name
NGF beta
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10781-780
500 µg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (500µG)
Each (500µG) - $1,914.21
$1,914.21
Each (500µG)
$1,914.21
La quantité minimale de commande est de 1
Supplier Number: AF-450-01-500UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10781-780
Protein/peptide name
NGF beta
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10781-782
1 mg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (1mg)
Each (1mg) - $3,196.25
$3,196.25
Each (1mg)
$3,196.25
La quantité minimale de commande est de 1
Supplier Number: AF-450-01-1MG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10781-782
Protein/peptide name
NGF beta
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
Assay 1: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Assay 2: Determined by its ability to stimulate chick E9 DRG neurite outgrowth. The expected ED₅₀ is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁶ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT