Human Recombinant PDGF-AA (from E. coli)
À propos de cet article
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two α chains (250 total amino acids).
- Animal-free
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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- L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
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Product Details & Documents
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-AA is a 28.5 kDa disulfide-linked homodimer of two α chains (250 total amino acids).
- Animal-free
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
Spécifications
Spécifications
- Catalog No:
- 10771-706
- 10771-708
- 10771-710
- 10781-672
- 10781-674
- 10781-676
- 10781-678
- Protein/peptide name:
- PDGF-AA
- PDGF-AA
- PDGF-AA
- PDGF-AA
- PDGF-AA
- PDGF-AA
- PDGF-AA
- Protein synonyms:
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Glioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Species:
- Human
- Human
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- 5154 P04085
- 5154 P04085
- 5154 P04085
- 5154 P04085
- 5154 P04085
- 5154 P04085
- 5154 P04085
- Sequence:
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- SIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT
- Protease-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Y
- Animal-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Y
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- Biological activity:
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Purity:
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- Form:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Formulation:
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Molecular weight:
- 28.5 kDa
- 28.5 kDa
- 28.5 kDa
- 28.5 kDa
- 28.5 kDa
- 28.5 kDa
- 28.5 kDa
- Reconstitution instructions:
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage conditions:
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Shipping temperature:
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
Spécifications
Product Family Options
Informations sur le produit
- TailleOriginAvailabilityPrice
- Supplier Number: AF-100-13A-2UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10771-706Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-10UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10771-708Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-50UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10771-710Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-100UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-672Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-250UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-674Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-500UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-676Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: AF-100-13A-1MGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10781-678Protein/peptide namePDGF-AAProtein synonymsGlioma-Derived Growth Factor (GDGF)|Platelet-Derived Growth Factor-AA|Osteosarcoma-Derived Growth Factor (ODGF)Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID5154 P04085SequenceSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPTProtease-freeYAnimal-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.5 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient
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