Human Recombinant CDNF (from E. coli)

Human Recombinant CDNF (from <i>E. coli</i>)

CDNF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote survival, growth and function of dopamine-specific neurons. CDNF and its structural homolog, MANF, each contain an N-terminal saposin-like lipid binding domain, and a carboxyl-terminal domain, which is not homologous to previously characterized protein structures. CDNF and MANF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson’s disease. Recombinant Human CDNF is an 18.5 kDa protein consisting of 162 amino acids, including 8 cysteine residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

Catalog No:
10781-194
10781-196
10781-198
10781-200
10781-202
10781-204

Protein/peptide name:
CDNF
CDNF
CDNF
CDNF
CDNF
CDNF

Protein synonyms:
ARMETL1|Cerebral Dopamine Neurotrophic Factor
ARMETL1|Cerebral Dopamine Neurotrophic Factor
ARMETL1|Cerebral Dopamine Neurotrophic Factor
ARMETL1|Cerebral Dopamine Neurotrophic Factor
ARMETL1|Cerebral Dopamine Neurotrophic Factor
ARMETL1|Cerebral Dopamine Neurotrophic Factor

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Protein Function:
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors

Species:
Human
Human
Human
Human
Human
Human

Source:
E. coli
E. coli
E. coli
E. coli
E. coli
E. coli

Conjugation:
Unconjugated
Unconjugated
Unconjugated
Unconjugated
Unconjugated
Unconjugated

Gene ID:
441549 Q49AH0
441549 Q49AH0
441549 Q49AH0
441549 Q49AH0
441549 Q49AH0
441549 Q49AH0

Sequence:
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL

Protease-free:
Y
Y
Y
Y
Y
Y

Endotoxin level:
Low
Low
Low
Low
Low
Low

Endotoxin content:
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg

Biological activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.

Purity:
0.98
0.98
0.98
0.98
0.98
0.98

Form:
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized

Formulation:
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.

Molecular weight:
18.5 kDa
18.5 kDa
18.5 kDa
18.5 kDa
18.5 kDa
18.5 kDa

Reconstitution instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.

Storage conditions:
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.

Shipping temperature:
Ambient
Ambient
Ambient
Ambient
Ambient
Ambient

Product Family Options

Taille
Origin
10781-194
5 μg
US

Each (5µG)
Each (5µG) - $228.96
$228.96
Each (5µG)
$228.96
Minimum order quantity is 1
: 450-05-5UG

Specifications
Cat. No.
10781-194
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10781-196
25 μg
US

Each (25µG)
Each (25µG) - $582.62
$582.62
Each (25µG)
$582.62
Minimum order quantity is 1
: 450-05-25UG

Specifications
Cat. No.
10781-196
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10781-198
100 μg
US

Each (100µG)
Each (100µG) - $1,716.42
$1,716.42
Each (100µG)
$1,716.42
Minimum order quantity is 1
: 450-05-100UG

Specifications
Cat. No.
10781-198
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10781-200
250 μg
US

Each (250µG)
Each (250µG) - $2,787.04
$2,787.04
Each (250µG)
$2,787.04
Minimum order quantity is 1
: 450-05-250UG

Specifications
Cat. No.
10781-200
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10781-202
500 μg
US

Each (500µG)
Each (500µG) - $4,788.08
$4,788.08
Each (500µG)
$4,788.08
Minimum order quantity is 1
: 450-05-500UG

Specifications
Cat. No.
10781-202
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10781-204
1 mg
US

Each (1mg)
Each (1mg) - $7,969.24
$7,969.24
Each (1mg)
$7,969.24
Minimum order quantity is 1
: 450-05-1MG

Specifications
Cat. No.
10781-204
Protein/peptide name
CDNF
Protein synonyms
ARMETL1|Cerebral Dopamine Neurotrophic Factor
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
441549 Q49AH0
Sequence
MQEAGGRPGA DCEVCKEFLN RFYKSLIDRG VNFSLDTIEK ELISFCLDTK GKENRLCYYL GATKDAATKI LSEVTRPMSV HMPAMKICEK LKKLDSQICE LKYEKTLDLA SVDLRKMRVA ELKQILHSWG EECRACAEKT DYVNLIQELA PKYAATHPKT EL
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
18.5 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient