Human Recombinant IL6 (from E. coli)

Human Recombinant IL6 (from <i>E. coli</i>)

IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6Rα and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.Manufactured using all Animal-Free reagents.

Carrier free
Animal-free

PVPPGEDSKD VAAPHRQPLT SSERIDKQIR YILDGISALR KETCNKSNMC ESSKEALAEN NLNLPKMAEK DGCFQSGFNE ETCLVKIITG LLEFEVYLEY LQNRFESSEE QARAVQMSTK VLIQFLQKKA KNLDAITTPD PTTNASLLTK LQAQNQWLQD MTTHLILRSF KEFLQSSLRA LRQM

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

: For research use only. Not for use in diagnostic or therapeutic procedures.

Carrier free
Animal-free

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

: For research use only. Not for use in diagnostic or therapeutic procedures.

Catalog No:
10778-280
10778-282
10778-284
10778-286
10778-288
10778-290
10778-292

Protein/peptide name:
IL6
IL6
IL6
IL6
IL6
IL6
IL6

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Species:
Human
Human
Human
Human
Human
Human
Human

Source:
E. coli
E. coli
E. coli
E. coli
E. coli
E. coli
E. coli

Animal-free:
Y
Y
Y
Y
Y
Y
Y

Endotoxin content:
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).
<0.1 ng/μg of protein (<1 EU/μg).

Biological activity:
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.

Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Formulation:
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized

Storage conditions:
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C
−20 °C

Shipping temperature:
RT
RT
RT
RT
RT
RT
RT

Product Family Options

Taille
Origin
10778-280
5 µg
US

Each (5µG)
Each (5µG) - $311.46
$311.46
Each (5µG)
$311.46

: AF-200-06-5UG

Specifications
Cat. No.
10778-280
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-282
20 µg
US

Each (20µG)
Each (20µG) - $704.09
$704.09
Each (20µG)
$704.09

: AF-200-06-20UG

Specifications
Cat. No.
10778-282
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-284
50 µg
US

Each (50µG)
Each (50µG) - $1,276.64
$1,276.64
Each (50µG)
$1,276.64

: AF-200-06-50UG

Specifications
Cat. No.
10778-284
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-286
100 µg
US

Each (100µG)
Each (100µG) - $2,215.54
$2,215.54
Each (100µG)
$2,215.54

: AF-200-06-100UG

Specifications
Cat. No.
10778-286
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-288
250 µg
US

Each (250µG)
Each (250µG) - $3,062.94
$3,062.94
Each (250µG)
$3,062.94

: AF-200-06-250UG

Specifications
Cat. No.
10778-288
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-290
500 µg
US

Each (500µG)
Each (500µG) - $5,237.98
$5,237.98
Each (500µG)
$5,237.98

: AF-200-06-500UG

Specifications
Cat. No.
10778-290
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT
10778-292
1 mg
US

Each (1mg)
Each (1mg) - $8,750.67
$8,750.67
Each (1mg)
$8,750.67

: AF-200-06-1MG

Specifications
Cat. No.
10778-292
Protein/peptide name
IL6
Protein/peptide type
Recombinant
Species
Human
Source
E. coli
Animal-free
Y
Endotoxin content
<0.1 ng/μg of protein (<1 EU/μg).
Biological activity
The ED₅₀ was determined by the dose-dependent stimulation of the proliferation of the IL-6 dependent murine 7TD1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁷ units/mg.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation
Lyophilized
Storage conditions
−20 °C
Shipping temperature
RT