Human Recombinant sRANK (from E. coli)

Human Recombinant sRANK (from <i>E. coli</i>)

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À propos de cet article

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic. These dendritic cells then stimulate naïve T-cell proliferation, and promote the survival of RANK + T-cells. RANK is also expressed in a variety of tissues, including skeletal muscle, thymus, liver, colon, small intestine, and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis, and in dendritic cell-mediated T-cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget's disease of bone (PDB2). Recombinant Human sRANK Receptor is a 19.3 kDa polypeptide containing the TNFR-homologous, cysteine-rich portion of the extracellular domain of RANK receptor (175 amino acid residues).

: For research use only. Not for use in diagnostic or therapeutic procedures.

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L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
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Product Details & Documents

: For research use only. Not for use in diagnostic or therapeutic procedures.

Specifications for Product Family

Spécifications

Catalog No:
10774-170
10774-172
10774-174
10774-176
10774-178

Protein/peptide name:
sRANK
sRANK
sRANK
sRANK
sRANK

Protein synonyms:
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)

Protein/peptide type:
Recombinant
Recombinant
Recombinant
Recombinant
Recombinant

Protein Function:
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors
Cytokines and Growth Factors

Species:
Human
Human
Human
Human
Human

Source:
E. coli
E. coli
E. coli
E. coli
E. coli

Conjugation:
Unconjugated
Unconjugated
Unconjugated
Unconjugated
Unconjugated

Gene ID:
8792 Q9Y6Q6
8792 Q9Y6Q6
8792 Q9Y6Q6
8792 Q9Y6Q6
8792 Q9Y6Q6

Sequence:
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK

Protease-free:
Y
Y
Y
Y
Y

Endotoxin level:
Low
Low
Low
Low
Low

Endotoxin content:
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg
>0.1 ng/μg

Biological activity:
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.
Biological Activity tests can vary. Please refer to the Product CoA for information.

Purity:
0.98
0.98
0.98
0.98
0.98

Form:
Lyophilized
Lyophilized
Lyophilized
Lyophilized
Lyophilized

Formulation:
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.
Formulation can vary. Please refer to product CoA for information.

Molecular weight:
19.3 kDa
19.3 kDa
19.3 kDa
19.3 kDa
19.3 kDa

Reconstitution instructions:
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.
Reconstitution instructions can vary. Please refer to the product CoA for info.

Storage conditions:
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.
Store at –20 °C prior to reconstitution.

Shipping temperature:
Ambient
Ambient
Ambient
Ambient
Ambient

Spécifications

Product Family Options

Informations sur le produit

Taille
Origin
Availability
Price
10774-170
20 μg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (20µG)
Each (20µG) - $228.96
$228.96
Each (20µG)
$228.96

Supplier Number: 310-08-20UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10774-170
Protein/peptide name
sRANK
Protein synonyms
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
8792 Q9Y6Q6
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
19.3 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10774-172
100 μg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (100µG)
Each (100µG) - $558.42
$558.42
Each (100µG)
$558.42

Supplier Number: 310-08-100UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10774-172
Protein/peptide name
sRANK
Protein synonyms
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
8792 Q9Y6Q6
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
19.3 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10774-174
250 μg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (250µG)
Each (250µG) - $1,092.94
$1,092.94
Each (250µG)
$1,092.94

Supplier Number: 310-08-250UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10774-174
Protein/peptide name
sRANK
Protein synonyms
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
8792 Q9Y6Q6
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
19.3 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10774-176
500 μg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (500µG)
Each (500µG) - $1,751.89
$1,751.89
Each (500µG)
$1,751.89

Supplier Number: 310-08-500UG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10774-176
Protein/peptide name
sRANK
Protein synonyms
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
8792 Q9Y6Q6
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
19.3 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient
10774-178
1 mg
US
Log in pour la disponibilité
Log in pour la disponibilité
Each (1mg)
Each (1mg) - $2,923.49
$2,923.49
Each (1mg)
$2,923.49

Supplier Number: 310-08-1MG
L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.
Spécifications:
More
Specifications
Cat. No.
10774-178
Protein/peptide name
sRANK
Protein synonyms
TNFRSF11A|ODFR (Osteoclast Differentiation Factor Receptor)|CD265|TRANCE Receptor|ODAR (Osteoclast Differentiation and Activation Receptor)
Protein/peptide type
Recombinant
Protein Function
Cytokines and Growth Factors
Species
Human
Source
E. coli
Conjugation
Unconjugated
Gene ID
8792 Q9Y6Q6
Sequence
MQIAPPCTSE KHYEHLGRCC NKCEPGKYMS SKCTTTSDSV CLPCGPDEYL DSWNEEDKCL LHKVCDTGKA LVAVVAGNST TPRRCACTAG YHWSQDCECC RRNTECAPGL GAQHPLQLNK DTVCKPCLAG YFSDAFSSTD KCRPWTNCTF LGKRVEHHGT EKSDAVCSSS LPARK
Protease-free
Y
Endotoxin level
Low
Endotoxin content
>0.1 ng/μg
Biological activity
Biological Activity tests can vary. Please refer to the Product CoA for information.
Purity
0.98
Form
Lyophilized
Formulation
Formulation can vary. Please refer to product CoA for information.
Molecular weight
19.3 kDa
Reconstitution instructions
Reconstitution instructions can vary. Please refer to the product CoA for info.
Storage conditions
Store at –20 °C prior to reconstitution.
Shipping temperature
Ambient