Human Recombinant IGF-BP5 (from E. coli)
À propos de cet article
IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa, cysteine-rich, secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts, and osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5-overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition, and retarded muscle development. Recombinant Human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
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IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa, cysteine-rich, secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts, and osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5-overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition, and retarded muscle development. Recombinant Human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
Specifications for Product Family
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- Catalog No:
- 10770-654
- 10770-656
- 10770-658
- 10770-660
- 10770-662
- 10770-664
- Protein/peptide name:
- IGF-BP5
- IGF-BP5
- IGF-BP5
- IGF-BP5
- IGF-BP5
- IGF-BP5
- Protein synonyms:
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Insulin-like Growth Factor-Binding Protein 5|IBP-5
- Protein/peptide type:
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Recombinant
- Protein Function:
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Cytokines and Growth Factors
- Species:
- Human
- Human
- Human
- Human
- Human
- Human
- Source:
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- E. coli
- Conjugation:
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Unconjugated
- Gene ID:
- 3488 P24593
- 3488 P24593
- 3488 P24593
- 3488 P24593
- 3488 P24593
- 3488 P24593
- Sequence:
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- MLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVS
- Protease-free:
- Y
- Y
- Y
- Y
- Y
- Y
- Endotoxin level:
- Low
- Low
- Low
- Low
- Low
- Low
- Endotoxin content:
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- >0.1 ng/μg
- Biological activity:
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Biological Activity tests can vary. Please refer to the Product CoA for information.
- Purity:
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- 0.98
- Form:
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Lyophilized
- Formulation:
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Formulation can vary. Please refer to product CoA for information.
- Molecular weight:
- 28.6 kDa
- 28.6 kDa
- 28.6 kDa
- 28.6 kDa
- 28.6 kDa
- 28.6 kDa
- Reconstitution instructions:
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Reconstitution instructions can vary. Please refer to the product CoA for info.
- Storage conditions:
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Store at –20 °C prior to reconstitution.
- Shipping temperature:
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
- Ambient
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Informations sur le produit
- TailleOriginAvailabilityPrice
- Supplier Number: 100-05-5UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
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Specifications
Cat. No.10770-654Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 100-05-25UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10770-656Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 100-05-100UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10770-658Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 100-05-250UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10770-660Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 100-05-500UGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10770-662Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient - Supplier Number: 100-05-1MGL'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.10770-664Protein/peptide nameIGF-BP5Protein synonymsInsulin-like Growth Factor-Binding Protein 5|IBP-5Protein/peptide typeRecombinantProtein FunctionCytokines and Growth FactorsSpeciesHumanSourceE. coliConjugationUnconjugatedGene ID3488 P24593SequenceMLGSFVHCEP CDEKALSMCP PSPLGCELVK EPGCGCCMTC ALAEGQSCGV YTERCAQGLR CLPRQDEEKP LHALLHGRGV CLNEKSYREQ VKIERDSREH EEPTTSEMAE ETYSPKIFRP KHTRISELKA EAVKKDRRKK LTQSKFVGGA ENTAHPRIIS APEMRQESEQ GPCRRHMEAS LQELKASPRM VPRAVYLPNC DRKGFYKRKQ CKPSRGRKRG ICWCVDKYGM KLPGMEYVDG DFQCHTFDSS NVSProtease-freeYEndotoxin levelLowEndotoxin content>0.1 ng/μgBiological activityBiological Activity tests can vary. Please refer to the Product CoA for information.Purity0.98FormLyophilizedFormulationFormulation can vary. Please refer to product CoA for information.Molecular weight28.6 kDaReconstitution instructionsReconstitution instructions can vary. Please refer to the product CoA for info.Storage conditionsStore at –20 °C prior to reconstitution.Shipping temperatureAmbient
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