Primary Human Coronary Artery Endothelial Cells (HCAEC) are isolated from the coronary arteries (the right and the left coronary artery, including the anterior descending and the circumflex branches) from a single donor

• Von Willebrand factor (vWF) positive
• CD31 positive
• Smooth muscle alpha-actin negative

This product can be used in the following applications. Angiogenesis research, Atherosclerosis research, Oncology, Drug uptake studies, Cell-cell junction investigation, Inflammation studies.

They are crucially involved in the regulation of coronary blood flow and cardiac functions and are consequently useful for in vitro studies of diseases such as thrombosis, atherosclerosis, and hypertension. HCAEC are also suitable for studying functional vaso-dilators, such as prostacyclin, bradykinin, or nitric oxide.