Anti-MAP3K7 Rabbit Polyclonal Antibody
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Product Details & Documents
TAK1 Antibody: TAK1 (TGF-beta activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3. Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation, while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity.
Type: Primary
Antigen: MAP3K7
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Spécifications
- Taille:0.1 mg
- Western blot:Yes
- Clonality:Polyclonal
- Form:Liquid
- ImmunoFluorescence:Yes
- Storage temperature:TAK1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Antigen name:mitogen-activated protein kinase kinase kinase 7
- Gene ID:O43318
- Immunogen:TAK1 antibody was raised against a synthetic peptide corresponding to 14 amino acids near the amino-terminus of human TAK1 isoform a. The immunogen is located within amino acids 40 - 90 of TAK1.
- Tested applications:E, WB, IF
- Storage buffer:TAK1 Antibody is supplied in PBS containing 0.02% sodium azide.
- Purification:TAK1 Antibody is affinity chromatography purified via peptide column.
- Antibody type:Primary
- Isotype:IgG
- Host:Rabbit
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Cat. No.:89415-726
- Reactivity:Human|Rat|Mouse
- Antigen synonyms:MAP3K7
- Conjugation:Unconjugated
- Antigen symbol:MAP3K7
- ELISA:Yes
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Catalogue #: CA21905-026
Supplier: Kimberly-Clark