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- Size:1 Kit
- Storage conditions:−80 °C
- Application:Fluorescent Detection, HTS, Activity Assay
- Cat. no.:89156-484
- Supplier No.:AK417-0001
A QuantiZymeTM Assay System
The MMP-14 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay sytem designed to screen for inhibitors of matrix metalloproteinase-14 (MMP-14, membrane-type matrix metalloproteinase 1, MT1-MMP) using a quenched fluorogenic peptide: OmniMMPTM fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH. Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.