EX 527 ≥95%
1 mg
89147-900
: 270-437-M001
Potent cell permeable and metabolically stable specific inhibitor of hSIRT1 (IC50=98nM in vivo / IC50=38nM in vitro; compared to hSIRT2: IC50=19µM and hSIRT3: IC50=48µM) with no effect on human histone deacetylases (HDACs) class I and class II, nor NAD glycohydrolase (IC50>100µg). Inhibits the deacetylation of p53 (IC50=1µM).
- SIRT inhibitor
White to beige powder.
Soluble in DMSO (10mg/ml).
: 6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, EX-527, Selisistat
- :49843-98-3
- :C₁₃H₁₃ClN₂O
- :MFCD03009471
- :248.71 g/mol
- :Congélateur
- Taille:1 mg
KIMTECH SCIENCE® KIMWIPES™ Delicate Task Wipers, KIMBERLY-CLARK PROFESSIONAL®
#: CA21905-026
: Kimberly-Clark