E-76
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Product Details & Documents
Anticoagulant and antithrombotic peptides. Please see also the product family 'Hirudin Fragments and Analogs', the inhibitors N-1065, N-1215, N-1260, N-1565, and N-1970, and the anticoagulant anisindione, Q-1085.
The potent anticoagulant E-76, Acetyl-ALCDDPRVDRWYCQFVEG-amide, is an inhibitor of coagulation factor VIIa. It has been suggested that E-76 works by binding to an exosite on the factor VIIa protease domain, and non-competitively inhibits activation of factor X and amidolytic activity. E-76 has a well defined structure in solution determined by NMR spectroscopy that is similar to the X-ray crystal structure when complexed with factor VIIa and represents a new framework for the development of inhibitors for serine proteases.
Spécifications
Spécifications
- Taille:1 mg
- Cat. No.:H-4902.0001BA
- Molecular formula:C₉₇H₁₃₉N₂₇O₂₉S₂
- Protein/peptide name:E-76
- Storage conditions:–20 ± 5 °C
- Sequence:Ac-Ala-Leu-Cys-Asp-Asp-Pro-Arg-Val-Asp-Arg-Trp-Tyr-Cys-Gln-Phe-Val-Glu-Gly-NH₂
- Molecular weight:2211.47
Spécifications
#: CA21905-026
Supplier: Kimberly-Clark