Cyclo(-Leu-Pro)
À propos de cet article
Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.
Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry.
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Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.
Cyclo(Leu-Pro) showed antibacterial activity. Yan et al. observed that Cyclo(Leu-Pro) produced by Achromobacter xylosoxidans inhibited aflatoxin production by Aspergillus parasiticus. The diketopiperazine was shown to inhibit catecholamine release in vitro. It could play a role in the hypothalamic modulation of appetite suppressant circuitry.
Specifications for Product Family
Spécifications
Spécifications
- Catalog No:
- G-1750.0250BA
- G-1750.1000BA
- Protein/peptide name:
- Cyclo(-Leu-Pro)
- Cyclo(-Leu-Pro)
- CAS No.:
- 2873-36-1
- 2873-36-1
- MDL No.:
- MFCD00237617
- MFCD00237617
- Sequence:
- Cyclo(-Leu-Pro)
- Cyclo(-Leu-Pro)
- Molecular weight:
- 210.28
- 210.28
- Molecular formula:
- C₁₁H₁₈N₂O₂
- C₁₁H₁₈N₂O₂
- Storage conditions:
- –20 ± 5 °C
- –20 ± 5 °C
Spécifications
Product Family Options
Informations sur le produit
- TailleAvailabilityPrice
- Supplier Number: 4003115.0250L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
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Specifications
Cat. No.G-1750.0250BAProtein/peptide nameCyclo(-Leu-Pro)CAS No.2873-36-1MDL No.MFCD00237617SequenceCyclo(-Leu-Pro)Molecular weight210.28Molecular formulaC₁₁H₁₈N₂O₂Storage conditions–20 ± 5 °C - Supplier Number: 4003115.1000L'article nécessite un contrôle de la température pour le stockage et la livraison avec des frais supplémentaires. Il n'est pas éligible au retour pour des raisons de sécurité et de qualité. Tenez compte des exigences avant d'acheter.Spécifications:
More
Specifications
Cat. No.G-1750.1000BAProtein/peptide nameCyclo(-Leu-Pro)CAS No.2873-36-1MDL No.MFCD00237617SequenceCyclo(-Leu-Pro)Molecular weight210.28Molecular formulaC₁₁H₁₈N₂O₂Storage conditions–20 ± 5 °C
#: CA21905-026
Supplier: Kimberly-Clark