Sera (Serum)
Sera, whether bovine, human or from other sources, provides mammalian cells with the vital growth factors, lipids and more required for their growth in culture. The type of sera required is determined by both the cells being used and the media those cells require. Serum is a traditional supplement used in cell culture. Serum provides critical nutrients and growth factors needed by the cells for optimal growth. Fetal Bovine Serum (FBS) is the most common serum used for this purpose; however, there are other serum types used in the culture of cells. Serum alternatives are also available to support cell growth if applicable for the cell type. Avantor offers a wide variety of sera to meet the needs of cell culturists. Please select from the attributes below to find the sera options best suited to your application needs.
HyClone™ Fetal Bovine Serum Characterized (United States)
Supplier: Cytiva
Enhance growth of cells with U.S.sourced Cytiva HyClone™ Characterized Fetal Bovine Serum (FBS). More economical than Defined FBS, but meets the requirements of most discriminating cell culturists.
Expand 10 Items
HyClone™ Fetal Bovine Serum Characterized (Australia), HyClone Products (Cytiva)
Supplier: Cytiva
This premium HyCloneTM Fetal Bovine Australian-origin Serum is well-characterized, triple 100 nm filtered, virus-tested to 9 CFR standard, and traceability-certified (ISIA, Oritain).
Expand 2 Items
HyClone™ Newborn Bovine Calf Serum, US Origin, Cytiva
Supplier: Cytiva
Bovine calf serum products are excellent and cost-effective alternatives to fetal bovine serum (FBS). Bovine calf serum products contain exceptionally high levels of transferrin, which can provide three to four times as much available iron as FBS.
Expand 7 Items
HyClone™ FetalClone™ III serum, U.S. Origin, HyClone products (Cytiva)
Supplier: Cytiva
Origin is the most widely applicable of the FetalClone family and is designed to include fibroblasts in its applications.
Expand 5 Items
HyClone™ FetalClone™ I serum, U.S. origin, HyClone products (Cytiva)
Supplier: Cytiva
HyClone™ FetalClone® I is a foetal bovine serum alternative optimised for the growth of hybridomas with comparable IgG levels to those found in FBS.
Expand 1 Items
HyClone™ Fetal Bovine Sera Defined (United States), HyClone Products (Cytiva)
Supplier: Cytiva
Defined fetal bovine serum (FBS) is the highest quality of FBS available and is very widely used by those cell culturist who have a concern for viral contaminants and require an extensive biochemical profile. Defined FBS is filtered through multiple 40 nm (0.04 µm) pore-size related filters, which are the most retentive filters used in commercial FBS production. Over 50 components are analysed and the results are included on the biochemical assay.
Expand 5 Items
Normal Donkey Serum, Calbiochem®, MilliporeSigma
Supplier: MilliporeSigma
Normal carrier sera, produced from pooled lots of sera from healthy, non-immunized donkeys
Expand 1 Items
Calbiochem® Normal Goat Serum, MilliporeSigma
Supplier: MilliporeSigma
Normal carrier sera from healthy, non-immunized goats.
Expand 1 Items
HyClone™ Fetal Bovine Serum (United States), Super Low IgG, HyClone Products (Cytiva)
Supplier: Cytiva
Enhance cell culture growth with U.S.-sourced Cytiva HyClone Super Low IgG Fetal Bovine Serum (FBS).
Expand 6 Items
HyClone™ Fetal Bovine Serum, Canadian Origin, HyClone Products (Cytiva)
Supplier: Cytiva
HyClone Characterized Fetal Bovine Serum, Canadian origin, uses "True Pool" processing technology to ensure consistency in the quality of serum.
Expand 4 Items
HyClone™ Donor Equine Serum, U.S. origin, HyClone products (Cytiva)
Supplier: Cytiva
The animals are fed an enriched diet to ensure proper nutrition and are fasted prior to bleeding to reduce lipid concentration. The horses are bled in an enclosed facility that is specially equipped for aseptic collection. Coggins tests for equine infectious anemia are routinely performed on each horse.
Expand 6 Items
HyClone™ Newborn Bovine Calf Serum, New Zealand, HyClone products (Cytiva)
Supplier: Cytiva
Newborn bovine calf serum is a cost-effective alternative to foetal bovine serum (FBS). The serum is sourced from animals that are typically less than 10 days old.
Expand 3 Items
HyClone™ FetalClone™ III serum, U.S. origin
Supplier: Cytiva
Origin is the most widely applicable of the FetalClone family and is designed to include fibroblasts in its applications.
Expand 1 Items
HyClone™ Characterized Fetal Bovine Serum, CA Origin, HyClone products (Cytiva)
Supplier: Cytiva
A cost-efficient alternative to defined FBS, this high-quality Canadian serum is well-characterized.
Expand 3 Items
HyClone™ FetalClone™ I serum, U.S. origin, HyClone products (Cytiva)
Supplier: Cytiva
HyClone™ FetalClone® I is a foetal bovine serum alternative optimised for the growth of hybridomas with comparable IgG levels to those found in FBS.
Expand 4 Items
HyClone™ Standard Fetal Bovine Serum (FBS), U.S. Origin, Cytiva
Supplier: Cytiva
HyClone™ standard cell culture grade FBS is filtered through three sequential 100 µm (0,1 µm) pore-size rated filters.



