qPCR Assays
qPCR assays are used for many applications, including gene expression analysis, microRNA analysis, single nucleotide polymorphism, genotyping, copy number variation analysis, and even protein analysis. These assays are easy to implement and can be employed for both relative and absolute quantification methods. Successful qPCR assays require efficient and specific amplification of the product. A range of sample volumes can be tested simultaneously, with options to test multiple well-plates simultaneously in some models.
Crystal Digital PCR® Assay for ESR1 (11 Mutations)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific crystal flex probes and primers for the detection of ESRI mutations and its positive control. ESR1 (11 mutations) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify 11 mutations in the ESR1 gene using the ruby chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.
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Crystal Digital PCR® Assay for NRAS (G12D, drop-off G12-G13)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its positive control. NRAS (G12D, drop-off G12-G13) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in G12-G13 plus 1 mutation of the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.
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Crystal Digital PCR® Assay for HPV (ALB, HPV16/18/31/33/35/39/45/51/52/56/58)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of HPV genotypes and its Positive Control. HPV (ALB, HPV16/18/31/33/35/39/45/51/52/56/58) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 11 high risk HPV genotypes for cervical cancer plus a reference gene for human DNA quantification using the Ruby Chip.
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Crystal Digital PCR® Assay for ESR1 (17 Mutations)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of ESR1 mutations and its positive control. ESR1 (17 mutations) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 17 mutations in the ESR1 gene using the Ruby Chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.
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Crystal Digital PCR® Assay for NRAS (G12, G12D)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (G12, G12D) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.
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Crystal Digital PCR® Assay for PIK3CA (H1047, H1047R)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. The PIK3CA (H1047, H1047R) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.
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Crystal Digital PCR® Assay for HPV (ALB, HPV16/18/31/33/35)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of HPV genotypes and its positive control. HPV (ALB, HPV16/18/31/33/35) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 5 high risk HPV genotypes for cervical cancer plus a reference gene for human DNA quantification using the Ruby Chip.
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Crystal Digital PCR® Assay for TP53 (drop-off Y205-R209/V218-E221)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its positive control. TP53 (drop-off Y205-R209/V218-E221) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between Y205-R209 or V218-E221 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.
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Crystal Digital PCR® Assay for GSTP1 Methylation
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific crystal flex probes and primers for the detection of GSTP1 methylation and its positive control. The GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the GSTP1 promoter using the ruby chip. The GSTP1 promoter is implicated on the GSTP1 epigenetic silencing and dysregulation of detoxification pathways contributing to tumor initiation, progression, and drug resistance.
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Crystal Digital PCR® Assay for c-KIT (D816-D816V)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific crystal flex probes and primers for the detection of c-KIT mutations and its positive control. The c-KIT (D816, D816V) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the c-KIT gene using the Ruby Chip. c-KIT encodes for a receptor tyrosine kinase that plays a crucial role in cell signaling for processes including cell survival, proliferation, and differentiation.
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Crystal Digital PCR® Assay for EGFR (L858, L858R, L861Q)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of EGFR mutations and its Positive Control. The EGFR (L858, L858R, L861Q) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the EGFR gene using the Ruby Chip. EGFR encodes for the epidermal growth factor receptor, a protein that plays a crucial role in cell growth, proliferation, and differentiation.
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Crystal Digital PCR® Assay for C. albicans
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of C. albicans and its Positive Control. C. albicans Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 16 genes (1 gene per chromosome) of Candida albicans using the Ruby Chip. Candida albicans is a common yeast within the human gastrointestinal microbiota. Under certain conditions, it can become pathogenic leading to infections.
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Crystal Digital PCR® Assay for MYD88 (L265, L265P)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of MYD88 mutations and its positive control. The MYD88 (L265, L265P) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the MYD88 gene using the Ruby Chip. MYD88 encodes the MYD88 protein, which is an adaptor protein essential for transmitting signals in the immune system, mediating responses to infections, and modulating inflammation and cell survival.
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Crystal Digital PCR® Assay for PIK3CA (H1047, H1047L)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. The PIK3CA (H1047, H1047L) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.
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Crystal Digital PCR® Assay for NRAS (Q61, Q61R)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its positive control. NRAS (Q61, Q61R) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.
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Crystal Digital PCR® Assay for KRAS (drop-off G12-G13)
Supplier: STILLA TECHNOLOGIES, INC.
Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 of the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.
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