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Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: Hit8a]

Anti-CD8A Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: Hit8a]

Supplier: Tonbo Biosciences

The Hit8a antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

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TECHREF® H-2358 Sample Cells Single-Open Ended

TECHREF® H-2358 Sample Cells Single-Open Ended

Supplier: Tech Ref

TECHREF® H-2358 Sample Cells can be used in all models of Horiba and single-load XOS XRF analyzers.

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Demonstration Electric Meters

Demonstration Electric Meters

 

Supplier: Wards

Large, lightweight meters, ideal for classroom demonstrations.

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DRG® Candida albicans IgG ELISA, DRG International, Inc.

DRG® Candida albicans IgG ELISA, DRG International, Inc.

Supplier: DRG International

An enzyme immunoassay for the qualitative and semiquantitative determination of IgG-class antibodies to Candida albicans in serum.

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Anti-GRIN2B Rabbit Polyclonal Antibody

Anti-GRIN2B Rabbit Polyclonal Antibody

Supplier: Prosci

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death. Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged, memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.

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Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: Hit8a]

Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: Hit8a]

Supplier: Tonbo Biosciences

The Hit8a antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

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Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: SK1]

Anti-CD8A Mouse Monoclonal Antibody (violetFluor® 450) [clone: SK1]

Supplier: Tonbo Biosciences

The SK1 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

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Climate Chambers ICH Series, Memmert

Climate Chambers ICH Series, Memmert

Supplier: Memmert

Memmert stability chambers are constructed of stainless steel inside and out. The ICH L stability chamber will save energy and perform well for any project.

    
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EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), Premium Grade, Pierce™

EDC-HCl (N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride), Premium Grade, Pierce™

Supplier: Thermo Scientific

Thermo Scientific Pierce Premium Grade EDC is our highest quality formulation of this popular carbodiimide crosslinker, specially characterized for applications where product integrity and risk minimization are paramount.

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Metal-In Static Shielding Bags, 1000 Series, SCS, Desco Industries

Metal-In Static Shielding Bags, 1000 Series, SCS, Desco Industries

Supplier: Desco

Transparent, metal-in static shielding bags are designed to provide a static safe environment for ESD sensitive electronic devices.

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Anti-CD8A Rat Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: 53-6.7]

Anti-CD8A Rat Monoclonal Antibody (PerCP (Peridinin-Chlorophyll Protein Complex)-Cy5.5®) [clone: 53-6.7]

Supplier: Tonbo Biosciences

The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

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Anti-TJP1 Rabbit Polyclonal Antibody

Anti-TJP1 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

ZO-1, also called TJP1, belongs to the MAGUK family. This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. ZO-1 plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells. ZO1 may be associated the following disorders; celiac desease, congenital nephrotic syndrome finnish type, and macular degeneration. Anti-ZO-1 Antibody is useful for researchers interested in Apoptosis Research and Insulin Research.

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Planet-Safe® Cell Culture Dishes

Supplier: Diversified Biotech

100% Plant-Based Planet-Safe® microplates are made from PLA, a plant-based resin derived from non-GMO sustainably cultivated sugarcane.

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J&W VF-200ms Columns, Agilent Technologies

J&W VF-200ms Columns, Agilent Technologies

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA

Uniquely selective for high dipole-moment compounds such as ketones, aldehydes, nitro- or chloro-containing compounds, PAHs, unsaturated compounds, silanes, and CFCs.

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Pierce™ Protein Stabilizing Cocktail, Thermo Scientific

Pierce™ Protein Stabilizing Cocktail, Thermo Scientific

Supplier: Thermo Scientific

A versatile stabilizing solution that increases the shelf-life of purified or partially purified proteins during routine storage.

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C-Chip Disposable Hemacytometer, Electron Microscopy Sciences

C-Chip Disposable Hemacytometer, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences

The world's first truly disposable Hemacytometer, the C-Chip offers precise volume control and is easy to use.

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