2714 Results for: "Shenandoah Biotechnology"

Supplier: Fujifilm Irvine Scientific

Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.

Supplier: Fujifilm Irvine Scientific

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

Supplier: Fujifilm Irvine Scientific

Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway.  IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules.

Supplier: Fujifilm Irvine Scientific

Stromal cell-derived factor-1 alpha (SDF-1 α), also called CXCL12a, is one of two SDF-1 splice variants made by a wide variety of cells upon stimulation by inflammatory cytokines such as TNF, IL-1, and LPS. SDF-1α signals through the G protein-coupled receptor CXCR4 to recruit activated leukocytes. Human and mouse SDF-1 α share 99% sequence identity.

Supplier: Fujifilm Irvine Scientific

Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells, and fibroblasts in response to interferon gamma (IFN-γ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto's thyroiditis, Graves' disease, and Type 1 diabetes mellitus.

Supplier: VWR

Off-white to light brown powder from Streptomyces griseus.

Supplier: Avantor

These bundles are everything you need to perform agarose gel electrophoresis.

Supplier: MilliporeSigma

N-Methyl-2-pyrrolidone (NMP) for peptide synthesis, Supelco®

Supplier: Fujifilm Irvine Scientific

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) expression in monocytes, and promotes type 2 T helper (Th2) cell-mediated immune responses. IL-19 production is upregulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.

Supplier: Fujifilm Irvine Scientific

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Supplier: Fujifilm Irvine Scientific

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Supplier: Fujifilm Irvine Scientific

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

Supplier: Thermo Scientific

Supplier: Thermo Scientific

Supplier: VWR

Tris (hydroxymethyl) aminomethane

Supplier: Thermo Scientific

Supplier: Thermo Scientific

Supplier: Avantor

The professional-grade equipment in the Advanced Electrophoresis Bundles comes in a variety of sizes for any lab or class.

Supplier: Fujifilm Irvine Scientific

Growth hormone (GH) is an important mitogenic growth factor that is synthesized, stored, and secreted by somatotropic cells of the anterior pituitary gland. GH stimulates growth, cell reproduction, and cell regeneration. In children, GH deficiencies can cause short stature, growth failure, and delayed sexual maturity. Adult GH deficiency presents with reduced lean body mass, increased adiposity, reduced muscle strength, and ultimately premature mortality. GH replacement therapy is used to treat many growth disorders, including Turner syndrome, chronic renal failure, and Prader–Willi syndrome.

Supplier: VWR International

The low voltage power supply is designed for electrophoresis.

Supplier: VWR International

Double the Voltage

Supplier: GENOSENSOR CORPORATION

The RNA virial infection RT-PCR kit is designed to introduce students to the RNA viral world and RT-PCR – an RNA amplification technology.

Supplier: GRANT USA INC.

The Multi mixer 1000 is designed for stirring liquids up to 20 litres.

Supplier: Wards

Economical Retort Bases with tapped rod hole made of powder-coated pressed steel.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Hydrochloric acid 5.0 N, Biotech Reagent, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Orthophosphoric acid 33% (w/w), Biotech Reagent, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Sodium hydroxide 1.0 N in aqueous solution, Biotech Reagent, J.T.Baker®

Supplier: AMPLYUS LLC

Fast and robust PCR-based GMO detection from your favorite foods.

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Sodium hydroxide solution 50%, Biotech Reagent, J.T.Baker®

Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Made from USP Water for injection (WFI) and Hydrochloric acid, NF.