45 Results for: "STILLA TECHNOLOGIES, INC."

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. The PIK3CA (H1047, H1047R) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of ESR1 mutations and its positive control. ESR1 (17 mutations) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 17 mutations in the ESR1 gene using the Ruby Chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.

Supplier: STILLA TECHNOLOGIES, INC.

The Ruby Chip features cutting-edge, patented microfluidic technology that integrates the entire digital PCR workflow into a single fully automation-compatible consumable.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61R, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of RAD51C Methylation and its positive control. The RAD51C methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the RAD51C promoter using the ruby chip. RAD51C gene is involved in DNA repair, particularly in the homologous recombination pathway for genome stability.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its Positive Control. TP53 (drop-off V272-A276/G280-R283) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or G280-R283 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12A, G12C, G12D, G12V, drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 plus 4 mutations in the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific crystal flex probes and primers for the detection of BRCA1/RAD51C/GSTP1 methylation and its positive control. The BRCA1/RAD51C/GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the BRCA1, RAD51C, and GSTP1 promoter using the ruby chip. Methylation of the BRCA1, RAD51C, and GSTP1 affects DNA repair mechanisms crucial for genome stability and dysregulation of detoxification pathways, both contributing to tumor initiation, progression, and drug resistance.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (drop-off V600-K601) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations codons V600 and K601 of the BRAF gene. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600E, drop-off V600) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in codons V600-K601 plus 1 mutation in the BRAF gene. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. The PIK3CA (H1047, H1047L, H1047R) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutation in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of TERT mutations and its Positive Control. TERT (Ref/SLC12A7/228T/C242T-C243T/C250T/TSN) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 3 mutations in the TERT gene using the Ruby Chip. Three references are detected and used to quantify TERT gene amplification: a reference on the TERT gene, a reference on a gene located on the same chromosome as TERT (SLC12A7) and a reference on a different chromosome (TSN).

Supplier: STILLA TECHNOLOGIES, INC.

Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. PIK3CA (Ref, H1047L, E542K, E545K, H1047R, N345K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 5 mutations in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.

Supplier: STILLA TECHNOLOGIES, INC.

The Sapphire Chip features cutting-edge, patented microfluidic technology that integrates the entire digital PCR workflow into a single consumable.