"Genscript"

Supplier: Genscript

The product is specific for ranibizumab.

Supplier: Genscript

Adeno-associated virus type 8 (AAV8) is a valuable vector for gene therapy. It is one member of the human parvovirus family which depends on co-infection with helper viruses such as adenovirus or herpes virus for efficient reproduction. AAV8 empty capsids are composed of three proteins, VP1, VP2 and VP3 with relative molecular masses of 87, 72 and 62 kDa respectively.

Supplier: Genscript

GenScript MonoRab™ DYKDDDDK tag antibody, mAb, rabbit specifically recognizes DYKDDDDK tags placed at C-terminal, N-terminal and internal regions of DYKDDDDK fusion proteins.

Supplier: Genscript

The product is specific for Nivolumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01847-40, Anti- Nivolumab Antibody (8G6G3D8), mAb, Mouse.

Supplier: Genscript

The product is specific for Bevacizumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01975-40, Anti-Bevacizumab Antibody (4H1), mAb, Mouse.

Supplier: Genscript

Infliximab with the brand name of Remicade, is a chimeric monoclonal IgG1 antibody. It binds to TNF-alpha, which is a key proinflammatory cytokine involved in chronic inflammatory diseases. Infliximab functions as TNF-alpha blocker to disrupt the interaction of TNF-alpha with its receptors. GenScript Anti-Infliximab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Infliximab.

Supplier: Genscript

GenScript MonoRab™ Rabbit Anti-Camelid VHH Cocktail [FITC] is specific for Camelid VHH antibody (Llama, Alpaca and Camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.

Supplier: Genscript

The product is specific for infliximab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A02040-40, anti-infliximab antibody (27A4), mAb, mouse.

Supplier: Genscript

The ToxinEraser™ endotoxin removal resin utilizes immobilized polymixin B to bind and remove pyrogens from solution.

Supplier: Genscript

The product is specific for Cetuximab. This antibody can’t block Cetuximab binding with EGFR (Z03202, EGFR, His, Human) in ELISA. The antibody is recommended as a capture antibody in a pharmacokinetic (PK) bridging assay with detection antibody GenScript, A01938-40, Anti-Cetuximab Antibody (18D5), mAb, Mouse.

Supplier: Genscript

Bevacizumab (Avastin) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of a number of types of cancers and a specific eye disease. Bevacizumab binds to a continuous epitope in VEGF, preventing interaction of VEGF with VEGFR on the surface of endothelial cells. It can be used to inhibit solid tumours growth and metastasis by weakening tumour angiogenesis.

Supplier: Genscript

The product is specific for daratumumab.

Supplier: Genscript

Eculizumab with trade name Soliris, is an FDA-approved drug to treat paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and neuromyelitis optica. Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5. Eculizumab specifically binds to the terminal complement component 5 or C5. Binding to this protein prevents the activation of a complement terminal complex, which is used to treat a number of autoimmune conditions.Anti-Eculizumab Antibody (13F5), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with eculizumab.

Supplier: Genscript

THE™ DYKDDDDK Tag antibody, mAb, Mouse recognizes DYKDDDDK; tags localized at the C-terminal, N-terminal and internal region of DYKDDDDK
tagged fusion proteins.

Supplier: Genscript

Adeno-associated virus (AAV) is a single-stranded DNA virus that commonly infects humans without pathology. Therefore, AAV can be engineered to deliver DNA to target cells as a vector for gene therapy. There are several serotypes including AAV type 1, 2, 5, 6, 8, 9, DJ and rh.1. Among them, AAV2 is the best characterized and most commonly used. Cap gene of AAV gives rise to three capsid proteins, VP1, VP2 and VP3, with molecular weight of 87, 72 and 62 kDa respectively. These capsid proteins assemble into a near-spherical protein shell of 60 subunits for AAV.

Supplier: Genscript

Secukinumab with brand name Cosentyx, is a human IgG1κ monoclonal antibody that binds to the protein interleukin (IL)-17A, and is marketed by novartis for the treatment of psoriasis, ankylosing spondylitis, and psoriatic arthritis. Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells. IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor. Anti-Secukinumab antibody (23E11), mAb, mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Secukinumab.