11486 Results for: "Enzo Life Sciences"

In mammals, TIR domain adapters, including Myd88, TIRAP, TICAM-1 (also called TRIF), and TRAM, act in Toll-like receptor (TLR) signaling pathway. The last member of this family called SARM (sterile and armadillo motifs) is highly conserved but has no known function in any organism. SARM is the only mammalian TIR-domain adapter proteins conserved in C. elegans, suggesting that SARM is the most ancient member of this class of signaling proteins. Overexpression of SARM fails to activate either NF-kB- or IRF-3-dependent reporter gene expression, two transcription factors that are sensitive to TLR signaling, suggesting that SARM is functionally distinct from other mammalian TIR domain-containing proteins.

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Anti-EDA-A1 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

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Anti-PIDD Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

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Anti-DCC Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG2a lambda

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Anti-FAS Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG2b

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Hamster Recombinant Grp78/BiP (from E. coli), Enzo Life Sciences

Supplier: Enzo Life Sciences

Produced in E. coli.

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Bradykinin

Supplier: Enzo Life Sciences

eNOS activator

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Blocking peptide for Adiponectin receptor 1 pAb Blocking Peptide

Supplier: Enzo Life Sciences

Synthetic peptide corresponding to aa 345-369 of human, mouse or rat adiponectin receptor 1 (AdipoR1).

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Angiotensin I/II (1-7)

Supplier: Enzo Life Sciences

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Anti-CD40L Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences

Host: Mouse, Isotype: IgG1

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Ikb Kinase Substrate,Biotin

Supplier: Enzo Life Sciences

This peptide sequence, RHDSGLDSMKD, is derived from the area surrounding serine 32 and serine 36 of IκBα, which is phosphorylated by IκB Kinase (IKK). The biotin allows the peptide to be used in IKK kinase assays with streptavidin-bound membranes.

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Protein Kinase Inhibitor

Supplier: Enzo Life Sciences

PKA inhibitor

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Crosstide, Enzo Life Sciences

Supplier: Enzo Life Sciences

Akt substrate

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Anti-ESR2 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Host: Rabbit

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Anti-CAV3 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

Host: Rabbit

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Artemisinin ≥98%

Supplier: Enzo Life Sciences

iNOS inhibitor

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Microcystis aeruginosa [D-Asp3] microcystin-LR

Supplier: Enzo Life Sciences

Microcystins are a group of cyclic heptapeptide hepatotoxins produced by a number of cyanobacterial genera. The most notable of which, and namesake, is the widespread genus Microcystis. Structurally, all microcystins consist of the generalized structure cyclo(-D-Ala1-X2-D-MeAsp3-Y4-Adda5-D-Glu6-Mdha7-). X and Y are variable L-amino acids, D-MeAsp is D-erythro-β-methylaspartic acid and Mdha is N-methyldehydroalanine. Adda is the cyanobacteria unique C20 β-amino acid 3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-deca-4,6-dienoic acid. Substitutions of the variable L-amino acids at positions 2 and 4 give rise to at least 21 known primary microcystin analogs and alterations in the other constituent amino acids result in more than 90 reported mycrocystins to date.

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Puerarin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

5-HT2c inhibitor

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Limonin ≥98% (by HPLC)

Supplier: Enzo Life Sciences

Carciogenesis inhibitor

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R-Sulforaphane ≥98% (by UHPLC)

Supplier: Enzo Life Sciences

Carciogenesis inhibitor

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Her2 Substrate

Supplier: Enzo Life Sciences

This peptide, GGMEDIYFEFMGGKKK, identified by screening a degenerate peptide library, is a substrate for several kinases, including HER-2/c-neu/erb-B-2, Tie-2, cFMS, and cKit.