9549 Results for: "Biotium"

Supplier: Biotium

GelRed™ and GelGreen™ are a new generation of fluorescent nucleic acid gel stains designed to replace the highly toxic ethidium bromide (EtBr)

Supplier: Biotium

Transferrin is a glycoprotein with homologous N-terminal and C-terminal iron-binding domains that binds up to two Fe(III)atoms for delivery to vertebrate cells through receptor-mediated endocytosis

Supplier: Biotium

Label your antibody with one of our superior CF® Dyes in 30 minutes without a purification step. Labeling tolerates many common buffer components including BSA and ascites.

Supplier: Biotium

Phosphotyrosine, Monoclonal antibody, Clone: PY20, Host: Mouse, Species reactivity: All species, Isotype: IgG2b, Conjugate: CF405S, Immunogen: Phosphotyrosine conjugated to KLH, Synonyms: P-Tyr, Application: Immunofluorescence, Size: 100uL

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF93, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 500uL

Supplier: Biotium

This MAb reacts with a protein of 20-30 kDa, identified as PGP 9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1). Initially, PGP 9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP 9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP 9.5 gene is believed to cause a form of Parkinson's disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Biotium

By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Biotium

Progesterone, Monoclonal antibody, Clone: 6-5E-3F, Host: Mouse, Species reactivity: All species, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Progesterone hemisuccinate conjugated to BSA, Synonyms: Pregn 4 ene 3 20 dione, Application: RIA, Size: 500uL

Supplier: Biotium

PLAP (Placental Alkaline Phosphatase), Monoclonal antibody, Clone: GM022, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, BSA-free, Immunogen: Recombinant full-length human ALPP protein, Application: Immunofluorescence, Immunohistology (formalin), Flow, Size: 50 uL

Supplier: Biotium

Plasma Cell Marker, Monoclonal antibody, Clone: 7B18), Host: Mouse, Species reactivity: Human, Isotype: IgG2a, Conjugate: CF647, Immunogen: Pancreatic cancer-related mucin, Synonyms: Plasma B cell, Plasmocytes, Application: Immunohistology (formalin), Size: 100uL

Supplier: Biotium

This antibody recognizes a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Supplier: Biotium

This antibody recognizes a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP This antibody recognizes germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF93, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 100uL

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF93, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 100uL

Supplier: Biotium

Proximal Nephrogenic Antigen / Renal Cell Carcinoma (RCC), Monoclonal antibody, Clone: PN-15, Host: Mouse, Species reactivity: Human, Horse, Isotype: IgG2b, kappa, Conjugate: purified, Immunogen: human renal cortical tissue, Size: 100uL

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF93, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 100uL

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF94, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 500uL

Supplier: Biotium

PLGF, Monoclonal antibody, Clone: PLGF94, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recombinant human PLGF protein, Synonyms: PGFL; PIGF; placental growth factor (PGF), Application: ELISA, Size: 500uL

Supplier: Biotium

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Supplier: Biotium

CD4 (clone SK3) is a validated mouse monoclonal antibody that recognizes CD4, a membrane glycoprotein of T lymphocytes. The antibody have been validated and optimized in-house for optimal performance.

Supplier: Biotium

Mouse monoclonal [CD19/SJ25C1] antibody that recognizes CD19, a transmembrane glycoprotein in B cells. The antibody belongs to the biotium choice list of select antibodies that have been validated and optimized in-house for optimal performance.

Supplier: Biotium

CD8a (clone SK1) is a validated mouse monoclonal antibody that recognizes CD8a, a transmembrane glycoprotein and co-receptor found in T cells. This antibody derived from the CD8 alpha chain. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.

Supplier: Biotium

CF® Dye alkynes react with azide groups via copper-catalyzed bioorthogonal cycloaddition. Can be used to fluorescently detect or label azide groups on target molecules. CF® Dye alkynes can also be used as building blocks to form fluorescent polymers.

Supplier: Biotium

CF® dye-dCTP can be used to synthesize probes for in situ hybridization, microarray, or to synthesize labeled DNA probes for in situ hybridization and nucleic acid blotting applications.

Supplier: Biotium

Annexin V fluorescent conjugates can be used to detect apoptotic cells. Annexin V is available conjugated to a wide variety of dyes.

Supplier: Biotium

Membrane-permeant form of Rhod-590 calcium indicator dye that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Rhod-590 AM ester itself does not bind Ca2 , but it is readily hydrolyzed to Rhod-590 by endogenous esterases once it enters cells.

Supplier: Biotium

DEAC-dUTP (diethylaminocoumarin-dUTP) can be used to synthesize fluorescently labeled DNA probes for in-situ hybridization, microarray or blotting techniques.

Supplier: Biotium

Potential applications of Biotin-CF® dye include detection of biotin binding sites and the degree of biotinylation of proteins, and for the measurement of avidin and streptavidin in crude biological samples. In addition, biotin-CF® dye can be used as a polar tracer by microinjection to study the morphology of cells. CF® dyes are very photostable which make them suitable for studies where prolonged exposure to light may be necessary.

Supplier: Biotium

Highly purified dNTPs (>99% by HPLC) in purified water. Each deoxynucleotide solution (dATP, dCTP, dGTP, dTTP) is provided in a separate vial at 100 mm.

Supplier: Biotium

CF®594, Truly the brightest deep red dye