"Bachem Americas"

Supplier: Bachem Americas

Sequence: H-Asn-OtBu

Supplier: Bachem Americas

Sequence: Z-Lys(Boc)-OH

Supplier: Bachem Americas

Antimicrobial peptides are produced by plants and most organisms throughout the animal kingdom including humans. Antimicrobial peptides protect against a broad range of infectious agents, as bacteria, fungi, and viruses. The amphibian skin is an especially rich source of antimicrobial peptides. See also the product families: Hepcidins LL-37 and Fragments Tuftsin and Analogs (subfamily).

Supplier: Bachem Americas

Sequence: H-α-Me-DL-His-OH · 2 HCl

Supplier: Bachem Americas

Sequence: H-Cys(StBu)-OH

Supplier: Bachem Americas

Enterotoxigenic E.coli are able to produce several toxic peptides which may cause acute diarrhea in humans and domestic animals. The E.coli heat-stable enterotoxin STp is syntheszied in vivo as a 72 amino acid precursor consisting of pre-, pro-, and mature region. Mature STp is composed of 18 amino acids containing three intramolecular disulfide bonds, which seem to be important for the correct conformation of the biologically active structure.

Supplier: Bachem Americas

Pepstatin A (isovaleryl-pepstatin), a low molecular weight inhibitor of acid proteases, e.g. pepsin, renin, cathepsin D, and plasmepsin II. For the Plasmodium falciparum aspartyl protease plasmepsin II, Hill et al determined an IC₅₀ of 0.1 nM.

Supplier: Bachem Americas

H-Tyr(tBu)-2-chlorotrityl resin (200-400 mesh) (Low Substitution) 5g, Substitution 0. 20-0. 49 mmol/g, Storage Condition: -20 +/- 5 degree C.

Supplier: Bachem Americas

Also known as dioxopiperazines, piperazine-2,5-diones or DKPs. Diketopiperazines may occur as by-products during peptide synthesis or during the degradation of peptides. These cyclic dipeptides have been detected as taste-modulating compounds in food, they often show biological activity. DKPs are valuable chiral synthons, employed e.g. in Schöllkopf's versatile bislactim ether approach. They also have found use as catalysts for enantioselective synthesis, e.g. in the asymmetric Strecker reaction. See also the TRH metabolite cyclo(-His-Pro), G-1745, and cyclo(-Asp-Phe), G-1695, the major degradation product of aspartame.

Supplier: Bachem Americas

Sequence: Fmoc-Sar-OH

Supplier: Bachem Americas

Sequence: Suc-Ala-Glu-Pro-Phe-pNA

Supplier: Bachem Americas

This amino-terminal fragment of substance P exerts depressor and bradycardic effects when applied to the nucleus tractus solitarius. It was also shown that this fragment, contrary to substance P, may reduce signs of opioid withdrawal in mice.

Supplier: Bachem Americas

Sequence: Z-Gly-Pro-Arg-AMC · HCl

Supplier: Bachem Americas

Sequence: Fmoc-Dap(Aloc)-OH

Supplier: Bachem Americas

A sensitive and highly specific substrate for a rapid assay of rat brain TRH-deamidating enzyme (prolyl endopeptidase). TRH-βNA is also hydrolyzed by another TRH-degrading enzyme, pyroglutamyl peptidase II (thyroliberinase), which seems to play a key role in terminating the biological activity of neuronally released TRH.

Supplier: Bachem Americas

H-6578 corresponds to the selective bradykinin B₂ receptor agonist labradimil.