1874 Results for: "Anaspec Inc"

Supplier: Anaspec Inc

This is a fluorescent kallikrein substrate, Abs/Em=353/442 nm.
Sequence:Z-FR-AMC
MW:612.6 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This peptide is Srctide with an N-terminal 5-FAM (Ex/Em=494/521 nm) label. Srctide is a substrate for many protein kinases, such as Blk, BTK, cKit, EPHA1, EPHB2, EPHB3, ERBB4, FAK, Flt3, IGF-1R, ITK, Lck, MET, MUSK, Ret, Src, TIE2, TrkB, VEGF-R1 (Flt-1) and VEGF-R2 (KDR).
Sequence:5-FAM-GEEPLYWSFPAKKK-NH2
MW:2037.3 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This peptide, a nuclear localization signal (NLS) peptide, is derived from the Large T antigen residues 47 to 56 (PKKKRKVEDP). It can be used to tag DNA. DNA tagged to this peptide efficiently translocates into the cell nucleus.
Sequence:PKKKRKVEDPYC
MW:1490.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This is a fluorescent (FAM)-labeled Angiotensin II peptide, Abs/Em=494/518 nm. FAM (carboxyfluorescein) exhibits better chemical and photo-stability than FITC.
Sequence: FAM-DRVYIHPF
MW: 1404.5 Da
% Peak area by HPLC: 95
Storage condition: -20°C

Supplier: Anaspec Inc

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components

Supplier: Anaspec Inc

The SensoLyte® Rh110 Elastase Assay Kit detects elastase activity using a fluorogenic peptide substrate. Upon elastase cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=496 /520 nm. The increase in fluorescence intensity is directly proportional to enzyme activity. The kit does not require any separation steps and can be used to continuously measure the kinetics of elastase. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from screening compounds.

Supplier: Anaspec Inc

Dyrktide is designed as the optimal substrate sequence efficiently phosphorylated by DYRK1A, which is a dual-specificity protein kinase that is thought to be involved in brain development.
Sequence:RRRFRPASPLRGPPK
MW:1791.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Removal of any preexisting structures in lyophilized stocks of Aβ-peptide is the critical initial step for controlled aggregation studies. HFIP has been shown to break down β-sheet structure, disrupt hydrophobic forces in aggregated amyloid preparations, and promotes α-helical secondary structure. HFIP treatment of lyophilized Aβ-peptide resulted in a dense, homogeneous preparation of unaggregated peptide and samples can be stored as peptide films. HFIP treated Aβ-peptide samples can be stored as peptide films and can be used in controlled aggregation studies.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 4514.1
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Supplier: Anaspec Inc

BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.
Sequence:EDIIRNIARHLAQVGDSMDR
MW:2309.6 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This peptide is a naturally occurring mutant form of the wild type (WT) beta-Amyloid 1 to 42 peptide. The E22Q 'Dutch' mutant, also known as HCHWA-D, is caused by a point mutation in the beta-Amyloid encoding gene, with Glu replaced by Gln at position 22. Dutch E22Q mutation in beta-Amyloid causes familial cerebrovascular amyloidosis with abundant diffused amyloid plaque deposits. E22Q mutant and WT peptides are both stable in 'collapsed coil' conformations. The E22Q fibrils are more toxic for vascular cells than the WT fibrils.
Sequence: DAEFRHDSGYEVHHQKLVFFAQDVGSNKGAIIGLMVGGVVIA
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Supplier: Anaspec Inc

Abltide is a peptide substrate for Abl Kinase (Abl protein tyrosine kinase), a partner in the gag-Abl fusion protein of the Abelson murine leukemia virus. Used in Western blot and kinase assay.
Sequence:KKGEAIYAAPFA-NH2
MW:1264.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This is a biotinylated synthetic peptide substrate for S6 kinase.
Sequence:Biotin-AKRRRLSSLRA-NH2
MW:1538.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.
Sequence:SRLSKVAPVIKARMMEYGTT
MW:2238.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Conantokin G (Con G) toxin is a 17-amino-acid competitive antagonist of N-methyl-D-aspartate (NMDA) receptors. It was isolated from the venom of Conus geographus and it belongs to a unique family of g-carboxyglutamic acid-containing Conus peptides.
Sequence:GE(Gla)(Gla)LQ(Gla)NQ(Gla)LIR(Gla)KSN-NH2
MW:2264.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

C-Phycocyanin (C-PC) occurs as the major phycobiliprotein in many cyanobacteria and as a secondary phycobiliprotein in some red algae. The pigment has a single visible absorption maximum between 615 and 620 nm and a fluorescence emission maximum at ~650 nm. Its molecular weight is between 70,000 and 110,000 daltons. The pigment is composed of two subunits, α and β, which occur in equal numbers, but the exact number of α and β pairs which make up the molecule may vary among the species. Both α and β subunits contain only the PCB chromophore. In addition to absorbing light directly, this intensely blue pigment accepts quanta from phycoerythrin by fluorescent energy transfer in organisms in which PE is present. The red fluorescence of C-PC is transferred to allophycocyanin (see 82000).

Supplier: Anaspec Inc

This peptide is a negative control for cGRGDSP
Sequence:Cyclo-[GRGESP]
MW:582 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This is amino acids 92 to 106 fragment of the myelin oligodendrocyte glycoprotein (MOG). Mice with MOG (92–106)-induced experimental autoimmune encephalomyelitis develop extensive B cell reactivity against secondary myelin antigens. This peptide is encephalitogenic in SJL mice, DA rats, and rhesus monkeys.
Sequence: DEGGYTCFFRDHSYQ
MW: 2973.2 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Supplier: Anaspec Inc

This peptide is amino acids 323 to 339 amidated fragment of ovalbumin (OVA), the H-2b-restricted OVA class II epitope. This peptide is recognized by many T cells because it contains multiple T cell epitopes. This OVA fragment contains a nested set of CD4+ T cell epitopes. OVA 323 to 339 can be presented by I-Ad in at least three binding registers. The residues 327 to 333 are critical for peptide binding to I-Ad.
Sequence: ISQAVHAAHAEINEAGR-NH2
MW: 1773 Da
% Peak Area by HPLC: ≥ 95%
Storage condition: -20°C

Supplier: Anaspec Inc

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components

Supplier: Anaspec Inc

The recombinant human a-synuclein (1-140) (GenBank Accession # NP_000336) was expressed and purified from E. coli and conjugated with the fluorescence dye HiLyte FluorTM 488. This protein is produced without affinity tag.
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.

Supplier: Anaspec Inc

SensoLyte® Luminescent Alkaline Phosphatase Assay Kit provides highly sensitive chemiluminescent substrate to quantify alkaline phosphatase activity in solutions, in cell extracts, in live cells.

Supplier: Anaspec Inc

7-Hydroxy-4-methylcoumarin-3-acetic acid, SE is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. It is widely used for preparing bioconjugates of blue fluorescence.

Supplier: Anaspec Inc

An inactive control for the integrin-binding peptide, GRGDTP.
Sequence:GRGESP
MW:601.6 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This peptide is a negative control for the cyclo (-RGDfK), the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family. This peptide has low affinity binding to integrin peptides.
Sequence:Cyclo(-RADfK-)
MW:617.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This tag peptide may be used to detect proteins and peptides, and to facilitate functional analysis of proteins of interest.
Sequence:MEYPYDVPDYAAEYPYDVPDYAAEYPYDVPDYAAKLE
MW:4372.7 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

This 10-amino acid peptide epitope tag from hemophilus influenza is recognized by the common monoclonal antibody 12Ca5.
Sequence:CYPYDVPDYA
MW:1205.3 Da
% peak area by HPLC:95
Storage condition:-20° C

Supplier: Anaspec Inc

Cathepsin G is the serine protease released by neutrophils upon their activation

Supplier: Anaspec Inc

Cell culture reagent for dissolving AM esters.

Supplier: Anaspec Inc

This peptide is b-Amyloid 17 to 24 amino acids fragment. Several lines of evidence indicate that a region centering around positions 17 to 20 amino acids is important for b-Amyloid fibril formation. Destabilization of a helix covering residues 11–24, in particular residues 17–24, is critical for alpha-helix to b-strand conversion and fibril formation.
Sequence: LVFFAEDV
Molecular Weight: 939.1 Da
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Supplier: Anaspec Inc

C-terminal sulfated and amidated octapeptide Cholecystokinin (sulfated CCK-8) has the full biological action of the full-length 33-amino acid long Cholecystokinin (CCK). CCK acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.
Sequence: D-Y(SO3H)-MGWMDF-NH2
MW: 1143.3 Da
% Peak area by HPLC: 95
Storage condition: -20° C