"76177-196"

Supplier: Bioss

Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf196 gene product has been provisionally designated C20orf196 pending further characterization.

Supplier: VWR International

Covering cryogenic needs for sensitive, irreplaceable biological samples.

Supplier: Genetex

PIAS2 (AA185-196) BLOCKING PEP

Supplier: Bioss

Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf196 gene product has been provisionally designated C20orf196 pending further characterization.

Supplier: ELPRO SERVICES, INC.

ELPRO's next generation of INDEPENDENT monitoring solutions for temperature measurement with external sensors. The ideal Cryo shipper data logger kit to simplify the storage and transport of your valuable products. A convenient 'pause alarm' feature allows users to temporarily turn off the alarming e.g. during cryogenic LN2 tank refills, but still maintain traceability. The data logger kit is reconfigurable and reusable for up to three years and are 100% GxP compliant.

Supplier: Thermo Fisher Scientific

Ideal for routine processing, these centrifuges combine exceptional capacity, ergonomics, and value with market-leading capabilities including unparalleled productivity and throughput, as well as exceptional ergonomics.

Supplier: Aven Tools

SPZ-50 Stereo Zoom Binocular Microscope 6.7 to 50x, max 200x with optional lenses on stand PLED with 60 eco friendly LED lights with dimmer. Focus mount has coarse and fine focusing for precise control. Large 200×284 mm base. Compact footprint helps save bench space.

Supplier: Thermo Fisher Scientific

The Thermo Scientific™ Megafuge ST1/ST1R Plus benchtop centrifuges offer intuitive controls and versatility for power at every turn.

Supplier: Thermo Fisher Scientific

Thermo Scientific™ X series centrifuge is a versatile general-purpose centrifuge for research applications, offering exceptional capacity, ergonomic design, and energy-efficient performance with GreenCool technology. Built for sustainability and higher productivity, it features an upgraded touchscreen interface for intuitive operation and optimized throughput across diverse laboratory workflows.

Supplier: Thermo Fisher Scientific

Process a range of general-purpose applications including cell culture, microplate, bioproduction, blood separation, and microbiology with the Thermo Scientific™ Multifuge™ X4 Pro Centrifuge series featuring our new touch screen technology, saves time and makes daily tasks easier.

Supplier: Thermo Fisher Scientific

Thermo Scientific^™ S series centrifuge is a high-performance general-purpose centrifuge designed for routine processing, offering exceptional capacity, ergonomic operation, and energy-efficient performance with GreenCool Technology. Its advanced design maximizes productivity and throughput while promoting sustainability, making it ideal for high-demand laboratory environments.

Supplier: Thermo Fisher Scientific

Thermo Scientific^™ S series centrifuge is a high-performance general-purpose centrifuge designed for routine processing, offering exceptional capacity, ergonomic operation, and energy-efficient performance with GreenCool Technology. Its advanced design maximizes productivity and throughput while promoting sustainability, making it ideal for high-demand laboratory environments.

Supplier: Thermo Fisher Scientific

Thermo Scientific™ X series centrifuge is a versatile general-purpose centrifuge for research applications, offering exceptional capacity, ergonomic design, and energy-efficient performance with GreenCool technology. Built for sustainability and higher productivity, it features an upgraded touchscreen interface for intuitive operation and optimized throughput across diverse laboratory workflows.

Supplier: Biosensis

The amyloid beta peptide is derived from the cleavage of the Amyloid precursor protein (APP) and varies in length from 39 to 43 amino acids. However, the form(s) of amyloid-beta peptide (Aβ) associated with the pathology characteristic of Alzheimer’s disease (AD) remains unclear. In particular, the neurotoxicity of intraneuronal Aβ accumulation is an area of considerable research and controversy principally because antibodies thought to be specific for Aβ have been shown to actually detect intraneuronal APP and not Aβ exclusively. MOAB-2 (mouse IgG2b) is a pan-specific, high-titer antibody to Aβ residues 1-4 as demonstrated by biochemical and immunohistochemical analyses (IHC), and is highly specific just to amyloid beta peptide. MOAB-2 did not detect APP or APP-CTFs in cell culture media/lysates (HEK-APPSwe or HEK APPSwe/BACE1) or in brain homogenates from transgenic mice expressing 5 familial AD (FAD) mutation (5xFAD mice). Using IHC on 5xFAD brain tissue, MOAB-2 immunoreactivity co-localized with C-terminal antibodies specific for Aβ40 and Aβ42. MOAB-2 did not co-localize with either N- or C-terminal antibodies to APP. In addition, no MOAB-2-immunreactivity was observed in the brains of 5xFAD/BACE-/- mice, although significant amounts of APP were detected by N- and C-terminal antibodies to APP, as well as by 6E10. In both 5xFAD and 3xTg mouse brain tissue, MOAB-2 co-localized with cathepsin-D, a marker for acidic organelles, further evidence for intraneuronal Aβ, distinct from Aβ associated with the cell membrane. MOAB-2 demonstrated strong intraneuronal and extra-cellular immunoreactivity in 5xFAD and 3xTg mouse brain tissues.