Human/Mouse/Rat Recombinant BMP-2 (from E. coli)
Supplier: VWR International
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About this item
Bone morphogenetic protein 2 (BMP-2) is a member of the bone morphogenetic protein (BMP) family and functions as a potent inducer of bone and cartilage development. BMP proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. Active BMP-2 consists of forming a homodimer or a heterodimer with a related BMP, such as BMP-7.
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- Low endotoxin
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BMP-2 signals through type I and type II receptor tyrosine kinases in conjuction with SMAD proteins to directly promote osteoblast differentiation. BMP-2 is also important during cardiac development and supports epicardial cell migration.
Caution:
For research use only.
Specifications
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:HumanMouseRat
- Storage conditions:At or below –20 °C
- Endotoxin content:Endotoxin LAL (EU/µg) ≤0.1
- Biological activity:Bioactivity assay: Alkaline phosphatase activity induced in ATDC-5 cells; ED₅₀ ≤250 ng/ml; Bioactivity ≥4.0×10³ units/mg
- Gene ID:P12643/P21274/P49001
- Reconstitution instructions:Sterile water at 0.1 mg/ml
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:Y
- Protein synonyms:BMP-2A
- Protein/peptide name:BMP-2 (AF)
- Purity:≥95%
- Molecular weight:13.0/26.1 kDa
- Sequence:MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR
- Endotoxin level:Low
- Formulation:0.1% Trifluoroacetic acid (TFA)
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
- Tested applications:Bioassay
Specifications
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