Mouse Recombinant IL-13 (from E. coli)

New Product

Mouse Recombinant IL-13 (from E. coli)

New Product

Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression.

High quality
Low endotoxin
Affordable

IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive.

For research use only.

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Mouse
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤1
Biological activity:
Bioactivity assay: TF-1 cell proliferation; ED₅₀ ≤10 ng/ml; Bioactivity ≥1.0×10⁵ units/mg
Gene ID:
P20109
Reconstitution instructions:
Sterile 20 mM HCl at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
NC30
Protein/peptide name:
IL-13
Purity:
≥95%
Molecular weight:
12.3 kDa
Sequence:
MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Endotoxin level:
Low
Formulation:
0.1% Trifluoroacetic acid (TFA)
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay