Human Recombinant CD40-Ligand (from E. coli)

New Product

Human Recombinant CD40-Ligand (from E. coli)

New Product

CD40-Ligand, or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40-Ligand binds and activates the CD40 receptor on antigen-presenting cells. CD40-Ligand stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion.

High quality
Low endotoxin
Affordable

CD40-Ligand also induces cytokine production and tumoricidal activity in peripheral blood monocytes. CD40-Ligand is a co-stimulator of activated T cell proliferation and inflammatory protein production.

For research use only.

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
–20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.1
Biological activity:
Bioactivity assay: Activity of HEK-blue™ CD40L cells; ED₅₀ ≤50 ng/ml; Bioactivity ≥2.0×10⁴ units/mg
Gene ID:
P29965
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
Y
Protein synonyms:
TNFSF5|TRAP|CD154|gp39|T-BAM
Protein/peptide name:
CD-40-Ligand (AF)
Purity:
≥95%
Molecular weight:
16.3 kDa
Sequence:
MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
Endotoxin level:
Low
Formulation:
10 mM Sodium phosphate, pH 7.5
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay