Human Recombinant FGF-Basic 147 (from E. coli)

Supplier: VWR International

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Supplier: VWR International

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About this item

Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic is a critical component for embryonic stem cell culture systems and is necessary for maintaining cells in an undifferentiated state. Degredation of the full length FGF-basic N-terminus results in a truncated FGF-basic 147aa protein, when the protein is isolated from biological sources. The N-terminus extensions influence the localization of FGF-basic within the cell, but do not affect the biological activity of FGF-basic. Therefore, there are no detectable differences in biological activity between the full length FGF-basic 154aa and the truncated FGF-basic 147aa recombinant proteins.

High quality
Low endotoxin
Affordable

Caution:

For research use only.

Specifications

Conjugation:
Unconjugated
Protein Function:
Cytokine
Protein/peptide type:
Recombinant
Source:
E. coli
Species:
Human
Storage conditions:
−20 °C
Endotoxin content:
Endotoxin LAL (EU/µg) ≤0.1
Biological activity:
Bioactivity assay: NR6R-3T3 cell proliferation; ED₅₀ ≤5 ng/ml; Bioactivity ≥2.0×10⁵ units/mg
Gene ID:
P09038
Reconstitution instructions:
Sterile water at 0.1 mg/ml
Endotoxin-free:
N
Carrier-free:
Y
Protease-free:
N
Animal-free:
N
Protein synonyms:
FGF2|HBGF-2|Prostatropin
Protein/peptide name:
FGF-Basic 147
Purity:
≥95%
Molecular weight:
16.5 kDa
Sequence:
#N/A
Endotoxin level:
Low
Formulation:
10 mM Sodium phosphate, 75 mM Sodium chloride, pH 7.5
Nuclease-free:
N
Grade:
RUO
Shipping temperature:
RT
Tested applications:
Bioassay