Human Recombinant HUMAN T REG CELL POLARIZING PB (from E. coli)
Catalog # 77753-608
Supplier: VWR International
New Product
CAS Number:
Specifications
- Pack type:Vial
- Conjugation:Unconjugated
- Protein Function:Cytokine
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:Each
- Storage conditions:At or below –20 °C
- Endotoxin-free:N
- Carrier-free:Y
- Protease-free:N
- Animal-free:N
- Protein/peptide name:T REG CELL POLARIZING PB
- Endotoxin level:Low
- Nuclease-free:N
- Grade:RUO
- Shipping temperature:RT
Specifications
About this item
Cytokines for polarizing T cells into T regulatory cells. T regulatory cells (Tregs) are a subset of T cells that suppress immune function. They are characterized by the expression of CD4, CD25 and Foxp3 and are known to produce immunosuppressive cytokines TGF-β 1 and IL-10.
- High quality
- Low endotoxin
- Affordable
Tregs can be cultured from naive CD4+ T cells by culturing them in the presence of IL-2 and TGF-β 1 with CD3 and CD28 stimulation. In some cases cells are also cultured with neutralizing antibodies to IL-4, IFNγ and IL-12 and/or retinoic acid.
Caution: For research use only.